82863-65-8

Basic information

• Product Name: Cyclo(Tyr-Leu)
• Synonyms: Cyclo(Tyr-Leu);3-(4-hydroxybenzyl)-6-isobutylpiperazine-2,5-dione;Cyclo(L-Tyr-L-Leu)
• CAS NO: 82863-65-8
• Molecular Formula: C₁₅H₂₀N₂O₃
• Molecular Weight: 276.3309
• Mol File: 82863-65-8.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Cyclo(Tyr-Leu)(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclo(Tyr-Leu)(82863-65-8)
• EPA Substance Registry System: Cyclo(Tyr-Leu)(82863-65-8)

Safety Data

• Hazardous Substances Data: 82863-65-8(Hazardous Substances Data)

Upstream product

• 968-21-8 H-Leu-Tyr-OH 
• 1080-06-4 L-Tyr-OMe 
• 13139-15-6 N-tert-butoxycarbonyl-L-leucine 
• 18658-65-6 N-tret-butoxycarbonyl-L-leucinyl-L-tyrosine methyl ester 
• 26307-85-7 L-leucinyl-L-tyrosine methyl ester hydrochloride 

Relevant articles and documents

Cyclic dipeptides exhibit potency for scavenging radicals

Twenty kinds of cyclic dipeptides containing l-leucine were synthesized, and their antioxidant activity against .OH and O2·- was investigated. Compounds possessing polar amino acid residues, such as Asp, Cys, Glu, Lys, Pro, Ser, and Trp, exhibited higher antioxidant activity against .OH than vitamin E. However, only cyclo(l-Cys-l-Leu) scavenged O2·-.

Conformations of cyclic peptides. II. Side-chain conformation and ring shape in cyclic dipeptides.

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