82872-99-9

Basic information

• Product Name: ethyl 3-(4-Methoxyphenoxy)propanoate
• Synonyms: ethyl 3-(4-Methoxyphenoxy)propanoate;methyl 3-(4-methoxyphenoxy)propanoate
• CAS NO: 82872-99-9
• Molecular Formula: C₁₂H₁₆O₄
• Molecular Weight: 224.25304
• Mol File: 82872-99-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 143-146 °C(Press: 1 Torr)
• Appearance: /
• Density: 1.083±0.06 g/cm3(Predicted)
• CAS DataBase Reference: ethyl 3-(4-Methoxyphenoxy)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 3-(4-Methoxyphenoxy)propanoate(82872-99-9)
• EPA Substance Registry System: ethyl 3-(4-Methoxyphenoxy)propanoate(82872-99-9)

Safety Data

• Hazardous Substances Data: 82872-99-9(Hazardous Substances Data)

Usage

Uses

methyl 3-(4-methoxyphenoxy)propanoate is a useful research reagent in the preparation of phenoxypropionic acid derivatives with nematocidal properties.

Upstream product

• 539-74-2 Ethyl 3-bromopropionate 
• 150-76-5 4-methoxy-phenol 
• 140-88-5 ethyl acrylate 
• 1122-95-8 sodium 4-methoxyphenolate 

Downstream Products

• 39223-40-0 3-(4-hydroxy-phenoxy)-propionic acid 
• 20811-60-3 3-(4-methoxyphenoxy)propanoic acid 

Relevant articles and documents

The synthesis and evaluation of phenoxyacylhydroxamic acids as potential agents for Helicobacter pylori infections

Two series of ω-phenoxy contained acylhydroxamic acids as novel urease inhibitors were designed and synthesized. Biological activity evaluations revealed that ω-phenoxypropinoylhydroxamic acids were more active than phenoxyacetohydroxamic acids. Out of these compounds, 3-(3,4-dichlorophenoxy)propionylhydroxamic acid c24 showed significant potency against urease in both cell free extract (IC50 = 0.061 ± 0.003 μM) and intact cell (IC50 = 0.89 ± 0.05 μM), being over 450- and 120-fold more potent than the clinically prescribed urease inhibitor AHA, repectively. Non-linear fitting of experimental data (V-[S]) suggested a mixed-type inhibition mechanism and a dual site binding mode of these compounds.