82878-62-4 Usage
Uses
Used in Pharmaceutical Synthesis:
Pyridine, 4-(difluoromethyl)(9CI) is utilized as a key intermediate in the development of pharmaceuticals. Its unique structure allows for the creation of new drug molecules with potential therapeutic effects. The difluoromethyl group can be strategically positioned to enhance the pharmacokinetic and pharmacodynamic properties of the resulting compounds, leading to improved efficacy and safety profiles.
Used in Agrochemical Production:
In the agrochemical industry, Pyridine, 4-(difluoromethyl)(9CI) serves as a crucial building block for the synthesis of various pesticides and herbicides. The incorporation of the difluoromethyl group can enhance the biological activity and selectivity of these agrochemicals, providing more effective and environmentally friendly solutions for crop protection.
Used as a Solvent:
Pyridine, 4-(difluoromethyl)(9CI) can also function as a solvent in chemical reactions. Its unique properties, such as polarity and hydrogen bonding capacity, make it suitable for dissolving a wide range of compounds and facilitating various chemical transformations.
Used in Chemical Research:
As an important building block in organic chemistry, Pyridine, 4-(difluoromethyl)(9CI) is frequently employed in research settings. It is used to explore new synthetic pathways, develop innovative chemical reactions, and investigate the properties of novel compounds. Its versatility and reactivity make it a valuable tool for advancing scientific knowledge and discovering new applications in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 82878-62-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,8,7 and 8 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 82878-62:
(7*8)+(6*2)+(5*8)+(4*7)+(3*8)+(2*6)+(1*2)=174
174 % 10 = 4
So 82878-62-4 is a valid CAS Registry Number.
82878-62-4Relevant academic research and scientific papers
Silica-supported silver nanoparticles as an efficient catalyst for aromatic C-H alkylation and fluoroalkylation
Khrizanforov, Mikhail N.,Fedorenko, Svetlana V.,Mustafina, Asiya R.,Kholin, Kirill V.,Nizameev, Irek R.,Strekalova, Sofia O.,Grinenko, Valeriya V.,Gryaznova, Tatiana V.,Zairov, Rustem R.,Mazzaro, Raffaello,Morandi, Vittorio,Vomiero, Alberto,Budnikova, Yulia H.
supporting information, p. 9608 - 9616 (2018/08/06)
The efficient catalysis of oxidative alkylation and fluoroalkylation of aromatic C-H bonds is of paramount importance in the pharmaceutical and agrochemical industries, and requires the development of convenient Ag0-based nano-architectures with high catalytic activity and recyclability. We prepared Ag-doped silica nanoparticles (Ag0/+@SiO2) with a specific nano-architecture, where ultra-small sized silver cores are immersed in silica spheres, 40 nm in size. The nano-architecture provides an efficient electrochemical oxidation of Ag+@SiO2 without any external oxidant. In turn, Ag+@SiO2 5 mol% results in 100% conversion of arenes into their alkylated and fluoroalkylated derivatives in a single step at room temperature under nanoheterogeneous electrochemical conditions. Negligible oxidative leaching of silver from Ag0/+@SiO2 is recorded during the catalytic coupling of arenes with acetic, difluoroacetic and trifluoroacetic acids, which enables the good recyclability of the catalytic function of the Ag0/+@SiO2 nanostructure. The catalyst can be easily separated from the reaction mixture and reused a minimum of five times upon electrochemical regeneration. The use of the developed Ag0@SiO2 nano-architecture as a heterogeneous catalyst facilitates aromatic C-H bond substitution by alkyl and fluoroalkyl groups, which are privileged structural motifs in pharmaceuticals and agrochemicals.
