828914-55-2Relevant academic research and scientific papers
A scalable synthesis of 1-cytosinyl-N-malayamycin A: A potent fungicide
Loiseleur, Olivier,Schneider, Hermann,Huang, Guobin,Machaalani, Roger,Selles, Patrice,Crowley, Patrick,Hanessian, Stephen
, p. 518 - 524 (2012/12/22)
A stereocontrolled synthesis of 1-cytosinyl-N-malayamycin A, an N-analogue of the naturally occurring malayamycin A with fungicidal activity, is reported. The approach was designed to rely solely on substrate control for introduction of the required stere
Total synthesis of N-malayamycin A and related bicyclic purine and pyrimidine nucleosides
Hanessian, Stephen,Huang, Guobin,Chenel, Caroline,Machaalani, Roger,Loiseleur, Olivier
, p. 6721 - 6734 (2007/10/03)
Methods are described for the total synthesis of bicyclic perhydrofuropyran nucleosides as N-analogues of the naturally occurring malayamycin A. Formation of the N-nucleosides relied on the activation of thioglycosides, proceeding via sulfonium intermedia
NOVEL 2,7-DIOXO-BICYCLO[4.3.0]NON-5-YL-UREA DERIVATIVES
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Page/Page column 37, (2010/02/10)
The present invention relates to novel fungicidal 2,7-dioxo-bicyclo[4.3.0] non-5-yl-urea derivatives, to processes for their preparation and to certain intermediate chemicals used in those processes. It also relates to the use of the compounds as biocides, to compositions containing biocidally effective amounts of the compounds and to methods of combating pathogens using the compounds. The invention encompasses 2,7-dioxo-bicyclo[4.3.0]non-5-yl-urea derivatives of formula (I) wherein R is H or C1-6alkyl (for example, methyl), the RO group is cis- or trans- to the NH2CONH group, R1 is H, formyl, C1-8alkylcarbonyl, C3-8cycloalkylcarbonyl, or optionally substituted benzoyl, and X is a N-linked heterocyclic group of the formula (II) or of the formula (III), wherein R2 is H, C1-4alkyl (especially methyl) or halo, or of the formula (IV): The compounds of formula I possess useful plant protecting properties and may advantageously be employed in agricultural practice for controlling or preventing the infestation of plants by phytopathogenic microorganisms, especially fungi.
