868617-20-3

Upstream product

• 864941-64-0 (2R,3R,4R,5S)-4-azido-3,5-bis(tert-butyldimethylsilanyloxy)-tetrahydropyran-2-carboxylic acid methoxymethylamide 
• 864941-82-2 (3R,4R,5S)-4-Azido-3,5-bis-(tert-butyl-dimethyl-silanyloxy)-tetrahydro-pyran-2-carboxylic acid methyl ester 
• 864941-65-1 (2R,3R,4R,5S)-4-azido-3,5-bis(tert-butyldimethylsilanyloxy)-tetrahydropyran-2-carbaldehyde 
• 864941-81-1 (3R,4R,5S)-4-Azido-3,5-dihydroxy-tetrahydro-pyran-2-carboxylic acid methyl ester 
• 864941-66-2 (1R,2'R,3'R,4'R,5'S)-1-[4'-azido-3',5'-bis(tert-butyldimethylsilanyloxy)-tetrahydropyran-2'-yl]-2,2-bis-phenylsulfanyl-ethanol 

Downstream Products

• 828914-55-2 (2R,3R,3aS,6S,7R,7aR)-7-azido-hexahydro-6-methoxy-2-(phenylthio)-2H-furo[3,2-b]pyran-3-ol 
• 828914-56-3 (2R,3R,3aR,6S,7R,7aR)-7-azido-hexahydro-6-methoxy-2-(phenylthio)-2H-furo[3,2-b]pyran-3-yl pivalate 
• 864941-84-4 (4R,4aR,7S,8R,8aR)-8-Azido-4-(bis-phenylsulfanyl-methyl)-7-methoxy-2,2-dimethyl-hexahydro-pyrano[3,2-d][1,3]dioxine 
• 828914-54-1 (1'R,2R,3R,4S,5S)-4-azido-2-(1'-hydroxy-2',2'-bis-phenylsulfanylethyl)-5-methoxy-tetrahydropyran-3-ol 
• 828914-61-0 [(2R,3R,3aS,6S,7R,7aR)-3-hydroxy-2-(2',4'-dioxo-3',4'-dihydro-2H-pyrimidin-1'-yl)-6-methoxy-hexahydrofuro[3,2-b]pyran-7-yl]-urea 
• 864941-60-6 (2R,3R,3aR,6S,7R,7aR)-7-azido-2-(6'-benzoylamino-purin-9'-yl)-6-methoxy-3-pivaloyloxy-hexahydrofuro[3,2-b]pyran 
• 864941-67-3 (4R,4aR,7S,8R,8aR)-8-Azido-4-(bis-phenylsulfanyl-methyl)-2,2-dimethyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-ol 

Relevant academic research and scientific papers

Total synthesis of N-malayamycin A and related bicyclic purine and pyrimidine nucleosides

Methods are described for the total synthesis of bicyclic perhydrofuropyran nucleosides as N-analogues of the naturally occurring malayamycin A. Formation of the N-nucleosides relied on the activation of thioglycosides, proceeding via sulfonium intermedia