828915-86-2

Upstream product

• 68-12-2 N,N-dimethyl-formamide 
• 828915-85-1 (S)-4-{(3S,4R)-4-(tert-Butyl-dimethyl-silanyloxy)-3-[2-(dimethyl-phenyl-silanyl)-ethyl]-6-methylene-cyclohex-1-enyl}-pentanoic acid 

Downstream Products

• 828915-88-4 (1R,5R,6S)-5-(tert-Butyl-dimethyl-silanyloxy)-6-[2-(dimethyl-phenyl-silanyl)-ethyl]-3-hydroxymethyl-2-((S)-4-hydroxy-1-methyl-butyl)-cyclohex-2-enol 
• 828915-89-5 (1R,5R,6S)-5-(tert-Butyl-dimethyl-silanyloxy)-6-[2-(dimethyl-phenyl-silanyl)-ethyl]-2-((S)-1-methyl-4-trityloxy-butyl)-3-trityloxymethyl-cyclohex-2-enol 
• 828915-90-8 (5R,6R)-5-(tert-Butyl-dimethyl-silanyloxy)-6-[2-(dimethyl-phenyl-silanyl)-ethyl]-2-((S)-1-methyl-4-trityloxy-butyl)-3-trityloxymethyl-cyclohex-2-enone 
• 828915-92-0 (1R,2R,3S)-2-[2-(Dimethyl-phenyl-silanyl)-ethyl]-4-((S)-1-methyl-4-trityloxy-butyl)-5-trityloxymethyl-cyclohex-4-ene-1,3-diol 
• 885483-14-7 (1R,2R,3R)-2-[2-(Dimethyl-phenyl-silanyl)-ethyl]-4-((S)-1-methyl-4-trityloxy-butyl)-5-trityloxymethyl-cyclohex-4-ene-1,3-diol 
• 828915-91-9 (5R,6R)-6-[2-(Dimethyl-phenyl-silanyl)-ethyl]-5-hydroxy-2-((S)-1-methyl-4-trityloxy-butyl)-3-trityloxymethyl-cyclohex-2-enone 
• 828915-97-5 2-Methyl-acrylic acid (3aR,4S,7aR)-3-methylene-5-((S)-1-methyl-4-trityloxy-butyl)-2-oxo-6-trityloxymethyl-2,3,3a,4,7,7a-hexahydro-benzofuran-4-yl ester 
• 828915-98-6 (Z)-2-Methyl-but-2-enoic acid (3aR,4S,7aR)-3-methylene-5-((S)-1-methyl-4-trityloxy-butyl)-2-oxo-6-trityloxymethyl-2,3,3a,4,7,7a-hexahydro-benzofuran-4-yl ester 
• 828915-95-3 (3aR,4S,7aR)-5-((S)-1-Methyl-4-trityloxy-butyl)-4-trimethylsilanyloxy-6-trityloxymethyl-3a,4,7,7a-tetrahydro-3H-benzofuran-2-one 
• 828915-93-1 (1R,2R,3S)-2-(2-Hydroxy-ethyl)-4-((S)-1-methyl-4-trityloxy-butyl)-5-trityloxymethyl-cyclohex-4-ene-1,3-diol 
• 828915-96-4 (3aS,4S,7aR)-4-Hydroxy-3-methylene-5-((S)-1-methyl-4-trityloxy-butyl)-6-trityloxymethyl-3a,4,7,7a-tetrahydro-3H-benzofuran-2-one 
• 828915-94-2 (3aS,4S,7aR)-4-Hydroxy-5-((S)-1-methyl-4-trityloxy-butyl)-6-trityloxymethyl-3a,4,7,7a-tetrahydro-3H-benzofuran-2-one 
• 885483-15-8 (1R,2R,3R)-2-(2-Hydroxy-ethyl)-4-((S)-1-methyl-4-trityloxy-butyl)-5-trityloxymethyl-cyclohex-4-ene-1,3-diol 

Relevant academic research and scientific papers

Enantioselective total synthesis of the highly oxygenated 1,10-seco-eudesmanolides eriolanin and eriolangin

Sultones of swing: A sultone served as the key intermediate in the first enantioselective total syntheses of the bioactive title compounds (see scheme), the absolute configuration of which is now established. Starting from 2-bromo-1-(2-furyl)ethanone, 24

A concise sultone route to highly oxygenated 1,10-seco-eudesmanolides - enantioselective total synthesis of the antileukemic sesquiterpene lactones (-)-eriolanin and (-)-eriolangin

Using a sultone as the key intermediate, the first enantioselective total synthesis of the antileukemic 1,10-seco-eudesmanolides (-)-eriolanin (1) and (-)-eriolangin (2) was achieved, which also established the hitherto unknown absolute configuration of t