828926-02-9 Usage
Uses
Used in Pharmaceutical Industry:
[1-(4-chloro-benzenesulfonyl)-3-oxo-piperazin-2-yl]-acetic acid is used as an Aldose Reductase inhibitor for the potential treatment of diabetic neuropathy. By inhibiting this enzyme, the compound may help alleviate the symptoms and complications associated with diabetes, particularly nerve damage.
Used in Cancer Treatment:
In the field of oncology, [1-(4-chloro-benzenesulfonyl)-3-oxo-piperazin-2-yl]-acetic acid has shown promise as a potential treatment for various types of cancer. Its specific mechanism of action and the cancers it targets are still under investigation, but its potential therapeutic properties make it a valuable compound for further research and development.
Used in Inflammation and Pain Management:
[1-(4-chloro-benzenesulfonyl)-3-oxo-piperazin-2-yl]-acetic acid has also demonstrated potential in managing inflammation and pain. Its exact role and efficacy in these applications are areas that require further exploration, but the initial findings suggest that it could be a useful addition to the arsenal of treatments available for these conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 828926-02-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,2,8,9,2 and 6 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 828926-02:
(8*8)+(7*2)+(6*8)+(5*9)+(4*2)+(3*6)+(2*0)+(1*2)=199
199 % 10 = 9
So 828926-02-9 is a valid CAS Registry Number.
828926-02-9Relevant academic research and scientific papers
3-Oxo-2-piperazinyl acetamides as potent bradykinin B1 receptor antagonists for the treatment of pain and inflammation
Chen, Jian Jeffrey,Nguyen, Thomas,D'Amico, Derin C.,Qian, Wenyuan,Human, Jason,Aya, Toshihiro,Biswas, Kaustav,Fotsch, Christopher,Han, Nianhe,Liu, Qingyian,Nishimura, Nobuko,Peterkin, Tanya A.N.,Yang, Kevin,Zhu, Jiawang,Riahi, Babak Bobby,Hungate, Randall W.,Andersen, Neil G.,Colyer, John T.,Faul, Margaret M.,Kamassah, Augustus,Wang, Judy,Jona, Janan,Kumar, Gondi,Johnson, Eileen,Askew, Benny C.
, p. 3384 - 3389 (2011/06/24)
The discovery of novel and highly potent oxopiperazine based B1 receptor antagonists is described. Compared to the previously described arylsulfonylated (R)-3-amino-3-phenylpropionic acid series, the current compounds showed improved in vitro potency and
Piperazine derivatives and methods of use
-
Page/Page column 42, (2008/06/13)
Selected compounds are effective for treatment of pain and diseases, such as inflammation mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving pain, inflammation, and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
