82898-77-9Relevant academic research and scientific papers
Copper-catalyzed synthesis of α-amino nitriles through methyl transfer from DMF to aromatic amines
Yuan, Zaifeng,Li, Na,Zhu, Chunyu,Xia, Chengfeng
, p. 2854 - 2857 (2018)
A copper-catalyzed activation of C(sp3)-H bonds of DMF at room temperature was developed, which results in methyl transfer to aromatic amines for efficient synthesis of exceedingly valuable α-amino nitriles. This process features excellent functional group tolerance, a broad substrate scope, and high activity under ambient conditions.
Reactions of N-Formyl Substituted Aminals with Trichloroacetyl Chloride
Boehme, Horst,Raude, Edgar
, p. 2050 - 2056 (2007/10/02)
N-Formyl substituted aminals of type 1 react with trichloroacetyl chloride to the glycinamide derived hydrochlorides 12 in addition to glycyl(trichloroacetyl)amines 13.This complicated reaction in which dialkylmethaniminium salts 7 and isonitrile 5 are in
