82902-47-4

Basic information

• Product Name: Piperidine, 1-acetyl-2-(1-methylethyl)- (9CI)
• Synonyms: Piperidine, 1-acetyl-2-(1-methylethyl)- (9CI)
• CAS NO: 82902-47-4
• Molecular Formula: C10H19NO
• Molecular Weight: 169.26396
• Product Categories: ACETYLGROUP
• Mol File: 82902-47-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 267.5±9.0 °C(Predicted)
• Appearance: /
• Density: 0.935±0.06 g/cm3(Predicted)
• PKA: -0.47±0.40(Predicted)
• CAS DataBase Reference: Piperidine, 1-acetyl-2-(1-methylethyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Piperidine, 1-acetyl-2-(1-methylethyl)- (9CI)(82902-47-4)
• EPA Substance Registry System: Piperidine, 1-acetyl-2-(1-methylethyl)- (9CI)(82902-47-4)

Safety Data

• Hazardous Substances Data: 82902-47-4(Hazardous Substances Data)

Upstream product

• 110-86-1 pyridine 
• 1068-55-9 isopropylmagnesium chloride 
• 75-36-5 acetyl chloride 

Relevant articles and documents

Regioselective Addition of Grignard Reagents to 1-Acylpyridinium Salts. A Convenient Method for the Synthesis of 4-Alkyl(aryl)pyridines

The addition of Grignard reagents to 1-acylpyridinium salts afforded 1-acyl-2-alkyl(aryl)-1,2-dihydropyridines and 1-acyl-4-alkyl(aryl)-1,4-dihydropyridines.The regioselectivity of this reaction, 1,2- vs. 1,4-addition, was examined and found to be dependent upon the structures of the Grignard reagent and the 1-acyl group.Pyridine, 2-picoline, and 3-picoline were studied, and in most cases, significant amounts of 1,4-addition occurred.When a catalytic amount of cuprous iodide was present, nearly exclusive 1,4-addition resulted.The crude 1,4-dihydropyridines were aromatized by heating with sulfur to provide 4-substituted pyridines and picolines in good yield and high isomeric purity.