82910-77-8Relevant academic research and scientific papers
Synthesis of β-amino alcohols via the reduction of lactamides derived from ethyl (2S)-lactate with borane-methyl sulfide
Lewis, Frank W.,Eichler, Matthias C.,Grayson, David H.
, p. 1923 - 1928 (2009)
Reactions of ethyl (2S)-lactate with various amines affords lactamides that are reduced with borane-methyl sulfide in the presence of boron trifluoride etherate to generate enantiomerically pure β-amino alcohols in good yield. Georg Thieme Verlag Stuttgart.
Catalytic asymmetric transfer hydrogenation of ketones using [Ru(p-cymene)Cl2]2 with chiral amino alcohol ligands
Deshpande, Sudhindra H.,Kelkar, Ashutosh A.,Gonnade, Rajesh G.,Shingote, Savita K.,Chaudhari, Raghunath V.
experimental part, p. 231 - 238 (2011/01/12)
Catalytic asymmetric transfer hydrogenation of aromatic alkyl ketones has been investigated using [Ru(p-cymene)Cl2]2 and new derivatives of β-amino alcohols synthesized from (S)-(-)-lactic acid and mandelic acid as ligands. Chiral secondary alcohols were obtained with good to excellent conversion (60-90%) and moderate to good enantioselectivities (40-86%).
