79-33-4 Usage
Chemical Properties
Crystalline Solid
Uses
Different sources of media describe the Uses of 79-33-4 differently. You can refer to the following data:
1. Occurs in small quantities in the blood and muscle fluid of man and animals. The lactic acid concentration increases in muscle and blood after vigorous activity. L-(+)-Lactic acid is also present in liver, kidney, thymus gland, human amniotic fluid, and o
2. It is most commonly used for fluid resuscitation after blood loss due to trauma, surgery, or burn injury. It is used in the agricultural, chemical, leather processing, pharmaceuticals, and cosmetics industries, used as an electroplating agent, food/feed additive, pH regulator, cleaning/washing agent, and tanning agent; used to flavor animal feeds; used as a solvent and intermediate in chemical production, as a pH regulator in fabric finishing, and in paints, coatings, soaps, and cleaning products; used to make large scale and fine chemicals, pulp-paper-paper products, food products, and plastic products, in mining, health services, agriculture-forestry-fishing, and building and construction work.
3. Lactic acid has been used:as a component in substrate solution II for lactate dehydrogenase reactionas an additive in storage solution Aas a supplement in the artificial gastric juice preparation for evaluation of degree of resistance Lactobacillus to the gastric stresses
Definition
ChEBI: An optically active form of lactic acid having (S)-configuration.
General Description
L-(+)-Lactic acid is the only naturally occurring lactic acid in humans and mammals. Commercially, few bacteria like Lactobacillus casei, L. delbrueckii, Streptococcus lactis produces L-Lactic acid by fermentation process. Lactic acid activates hydroxycarboxylic acid receptor, G-protein coupled receptor 81 (GPR81).
Flammability and Explosibility
Notclassified
Biochem/physiol Actions
L-(+)-Lactic acid is used as a substrate for lactic acid dehydrogenase and lactate oxidase.
Purification Methods
Purify lactic acid by fractional distillation at 0.1mm pressure, followed by fractional crystallisation from diethyl ether/isopropyl ether (1:1, dried with sodium). [Borsook et al. J Biol Chem 102 449 1933.] The solvent mixture, *benzene/diethyl ether (1:1) containing 5% pet ether (b 60-80o) has also been used. [Brin Biochemical Preparations 3 61 1953, Beilstein 3 IV 633.]
Check Digit Verification of cas no
The CAS Registry Mumber 79-33-4 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 7 and 9 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 79-33:
(4*7)+(3*9)+(2*3)+(1*3)=64
64 % 10 = 4
So 79-33-4 is a valid CAS Registry Number.
InChI:InChI=1/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)/t2-/m0/s1
79-33-4Relevant articles and documents
Asymmetric Synthesis of Optically Active 3-Cyclohexene-1-carboxylic Acid Utilizing Lactic Ester as a Chiral Auxiliary in the Diastereoselective Diels–Alder Reaction
Fujita, Ryunosuke,Hayashi, Wakana,Kubota, Shunichi,Nishi, Tatsuya,Nishiyama, Akira,Ochiai, Hidenori,Sasagawa, Miwa
supporting information, (2022/02/09)
The optically active 3-cyclohexene-1-carboxylic acid was synthesized through a TiCl4-catalyzed diastereoselective Diels–Alder reaction utilizing lactic acid ester as a chiral auxiliary, which can be removed by washing with H2O. The (S)- and (R)-isomers were both derived from easily available ethyl l-lactate.
γ-Valerolactone-introduced controlled-isomerization of glucose for lactic acid production over an Sn-Beta catalyst
Zhao, Xinpeng,Zhou, Zhimin,Luo, Hu,Zhang, Yanfei,Liu, Wang,Miao, Gai,Zhu, Lijun,Kong, Lingzhao,Li, Shenggang,Sun, Yuhan
supporting information, p. 2634 - 2639 (2021/04/22)
Combined experiments and density functional theory (DFT) calculations provided insights into the role of environment-friendly γ-valerolactone (GVL) as a solvent in the hydrothermal conversion of glucose into lactic acid (LA) over the post-synthesized Sn-Beta catalyst. By introducing 2.0 wt% GVL, a much higher yield of LA (72.0 wt%) was obtained than that in pure water (60.1 wt%) at 200 °C, 4 MPa N2, and 30 min in a batch reactor. The GVL effectively suppressed the isomerization of glucose into fructose in a controlled-transfer mode, resulting in a lower fructose concentration. Thermogravimetry-differential analysis and DFT calculations demonstrated that the competitive adsorption between GVL and glucose happened at the open Sn sites over the Sn-Beta catalyst, which led to a controlled isomerization rate in water. Further increasing the content of GVL to 20.0 wt%, the higher yield of LA (74.0 wt%) was attributed to the more efficient competitive adsorption while also inhibiting carbon deposition.
Epimerization-suppressed organocatalytic synthesis of poly-L-lactide in supercritical carbon dioxide under plasticizing conditions
Mase, Nobuyuki,Moniruzzaman,Yamamoto,Sato,Narumi, Tetsuo,Yanai, Hikaru
, (2019/08/06)
Herein, an efficient (>95% yield, >99.0% ee) Br?nsted acid-catalyzed synthetic method of poly-L-lactide (PLLA) in supercritical carbon dioxide (scCO2) under plasticizing conditions is presented. High-performance liquid chromatography analysis of the PLLA hydrolysis products indicated that, as opposed to the case of organic solvents, the use of a nucleophilic catalyst in scCO2 suppressed the epimerization. The highly stereochemically pure PLLA prepared by the developed method under metal-free conditions meets the criteria of medicinal/engineering applications.