82924-19-4

Basic information

• Product Name: ethyl (2R,4R)-5-hydroxy-4-methyl-2-(2-phenylethyl)pentanoate
• Synonyms: ethyl (2R,4R)-5-hydroxy-4-methyl-2-(2-phenylethyl)pentanoate
• CAS NO: 82924-19-4
• Molecular Weight: 264.365
• Mol File: 82924-19-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl (2R,4R)-5-hydroxy-4-methyl-2-(2-phenylethyl)pentanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (2R,4R)-5-hydroxy-4-methyl-2-(2-phenylethyl)pentanoate(82924-19-4)
• EPA Substance Registry System: ethyl (2R,4R)-5-hydroxy-4-methyl-2-(2-phenylethyl)pentanoate(82924-19-4)

Safety Data

• Hazardous Substances Data: 82924-19-4(Hazardous Substances Data)

Upstream product

• 82924-16-1 1-(4-phenylbutyryl)-L-prolinol 
• 82924-17-2 N-<(2R,4R)-5-(benzyloxy)-4-methyl-2-(2-phenylethyl)pentanoyl>-L-prolinol 
• 18496-54-3 phenylbutyric acid chloride 
• 82924-18-3 ethyl (2R,4R)-5-(benzyloxy)-4-methyl-2-(2-phenylethyl)pentanoate 

Downstream Products

• 82924-21-8 (2R,4R)-4-(ethoxycarbonyl)-2-methyl-4-(2-phenylethyl)butyryl chloride 
• 82950-76-3 1-<(2R,4R)-4-carboxy-2-methyl-4-(2-phenylethyl)butyryl>indoline-2(S)-carboxylic acid 
• 82924-14-9 1-<(2R,4R)-4-(ethoxycarbonyl)-2-methyl-4-(2-phenylethyl)butyryl>indoline-2(S)-carboxylic acid 
• 82924-20-7 ethyl hydrogen (2R,4R)-2-methyl-4-(2-phenylethyl)glutarate 

Relevant articles and documents

Angiotensin Converting Enzyme Inhibitors: 1-Glutarylindoline-2-carboxylic Acid Derivatives

The preparation of a series of 1-glutarylindoline-2(S)-carboxylic acid derivatives, 6a-v and 21a-c, is described.The above compounds were tested for inhibition of angiotensin converting enzyme.The structure-activity relationship of the series is also discussed.Compound 6u, the most potent member of the series, had an in vitro IC50 of 4.8*10-9 M.Compound 6v, an ethyl ester of 6u, lowered blood pressure 70 mm in spontaneous hypertensive rats at an oral dose of 30 mg/kg.