82933-21-9

Basic information

• Product Name: BZ-ASP-OME
• Synonyms: BZ-ASPARTIC ACID-OME;BZ-ASP-OME;BZO-ASP-OME;BENZOYL-L-ASPARTIC ACID ALPHA-METHYL ESTER;N-ALPHA-BENZOYL-L-ASPARTIC ACID-ALPHA-METHYL ESTER;Benzoyl-L-aspartic acid α- methyl ester;Benzoyl-L-aspartic acid α- methyl ester≥ 99%
• CAS NO: 82933-21-9
• Molecular Formula: C₁₂H₁₃NO₅
• Molecular Weight: 251.24
• Mol File: 82933-21-9.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: Store at RT.
• CAS DataBase Reference: BZ-ASP-OME(CAS DataBase Reference)
• NIST Chemistry Reference: BZ-ASP-OME(82933-21-9)
• EPA Substance Registry System: BZ-ASP-OME(82933-21-9)

Safety Data

• Hazardous Substances Data: 82933-21-9(Hazardous Substances Data)

Usage

Chemical Properties

White fluffy powder

Upstream product

• 50732-06-4 methyl benzoyl-L-methioninate 
• 3005-62-7 N^α-Benzoylhistidine Methyl Ester 
• 2717-75-1 N-benzoyl-L-tryptophan methyl ester 
• 67-56-1 methanol 

Downstream Products

• 296766-73-9 (1S)-N-[3-hydroxy-1-(hydroxymethyl)propyl]benzamide 
• 82933-22-0 N¹-benzoyl-5-(methoxycarbonyl)-2-imidazolidinone 
• 86555-45-5 (2S)-N-benzoyl-L-aspartic acid dimethyl ester 

Relevant articles and documents

Demonstration of Exclusive α-Peptidation at the Micellar Interface

Microreactors, dispersed in iso-octane, harboring water pools and crafted from AOT and co-surfactant condensing agent DODCI, exclusively direct α-peptidation, thus reversing the normal preference of glutamic acid and aspartic acid for side chain carboxyl group amidation.

L-METHIONINE OXIDATION: NOVEL AND UNANTICIPATED TRANSFORMATIONS WITH 4-tBUTYL IODOXYBENZENE

4-tButyl iodoxybenzene transforms Bz-Met-OMe to products arising from, S oxidation and C-H insertion followed by degradation.Z-Met(sulfoxide)-OMe is very effective in bringing about ester hydrolysis via intramolecular attack.The S oxidation to sulfoxides and then to sulfones can be monitored and controlled, proceeds with chiral retention, affects neither the peptide bond nor the protecting groups and has been further illustrated with,Z-Gly-Met-OMe, Z-Met-OMe and Z-S(benzyl)-Cys-OMe.