82950-64-9

Basic information

• Product Name: (+/-)-1,2-DIDECANOYLGLYCEROL
• Synonyms: DIDECANOIN;DICAPRIN;10:0 DG;1,2-DICAPRIN;1,2-DICAPRYL-SN-GLYCEROL;(+/-)-1,2-DIDECANOYLGLYCEROL;1,2-DIDECANOYL-RAC-GLYCEROL;1,2-didecanoyl-rac-glycerol (C10:0)
• CAS NO: 82950-64-9
• Molecular Formula: C23H44O5
• Molecular Weight: 400.59
• Mol File: 82950-64-9.mol
• Article Data: 28

Chemical Properties

• Appearance: /
• Storage Temp.: −20°C
• CAS DataBase Reference: (+/-)-1,2-DIDECANOYLGLYCEROL(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-1,2-DIDECANOYLGLYCEROL(82950-64-9)
• EPA Substance Registry System: (+/-)-1,2-DIDECANOYLGLYCEROL(82950-64-9)

Safety Data

• Hazardous Substances Data: 82950-64-9(Hazardous Substances Data)

Usage

General Description

(+/-)-1,2-DIDECANOYLGLYCEROL is a chemical compound that belongs to the class of glycerides, which are esters of glycerol and fatty acids. It is an important component of various natural oils and fats and is used in the production of pharmaceuticals, cosmetics, and food products. This chemical is a glyceride consisting of two decanoic acid molecules bound to a glycerol backbone. It is commonly used as an emollient and stabilizer in cosmetic products, and it also has potential applications in drug delivery systems due to its ability to enhance solubility and stability of certain drugs. Additionally, (+/-)-1,2-DIDECANOYLGLYCEROL has been studied for its potential role in modulating biological processes, such as lipid metabolism and immune function.

Upstream product

• 3436-44-0 1,2-didecanoyl-sn-glycero-3-phosphocholine 
• 621-71-6 capric acid triglyceride 
• 110-38-3 decanoic acid ethyl ester 
• 56-81-5 glycerol 
• 334-48-5 1-decanoic acid 
• 110-42-9 Methyl decanoate 
• 112-13-0 n-decanoyl chloride 
• 124-07-2 Octanoic acid 
• 3376-48-5 2-decanoyloxy-propane-1,3-diol 
• 103160-49-2 1,2-O,O'-bisdecanoyl-3-O-benzyl-rac-glycerol 
• 103160-49-2 1,2-di-O-decanoyl-3-O-benzyl-sn-glycerol 

Relevant articles and documents

Voriconazole derivative, synthesis thereof, and use thereof in long-acting preparation

The invention relates to a compound of formula (I), and a salt, an N-oxide, a quaternary ammonium and a stereoisomer thereof. R to R in the formula (I) are as defined in claims. The invention also relates to an intermediate for preparing the compound of formula (I), and a method for preparing the compound of formula (I). The invention further relates to a use of the compound of formula (I) as a drug especially used for preventing or treating fungal infection.

Posaconazole derivative, synthesis and application in prolonged action preparation thereof

The invention relates to a posaconazole derivative, synthesis and an application in a prolonged action thereof. The invention relates to a formula of a compound and salt, N-oxide, quaternary ammonium and stereoisomer of the compound, wherein R1-R8 are defined according to what is claimed. The invention also relates to a preparation formula of an intermediate body and a method of the compound. The invention further relates to a formula of an application of the compound as a drug, especially the application in preventing or treating fungal infection. The detailed formulas are in the specification.

Enzymatic synthesis of 1,3-dicaproyglycerol by esterification of glycerol with capric acid in an organic solvent system

In this work, the esterification of glycerol with capric acid catalyzed by an immobilized form of a 1,3-positionally selective lipase (Rhizomucor miehei) showed to be effective for the synthesis of 1,3-dicaprin in n-heptane as the reaction medium. The effects of the reaction parameters were studied using an experimental factorial design of three factors and three levels with two central points. The selected experimental variables were amount of glycerol adsorbed on silica gel (G), biocatalyst load (E) and reaction temperature (T), and the response variables were total conversion of capric acid, acylglycerol fractions, selectivity and yield of dicaprin, and acyl migration reaction. The range of each parameter was selected as follows: G = 50-250 mg, E = 20-40 mg and T = 40-60 C. At optimum conditions 73% capric acid conversion was achieved, with 76% dicaprin selectivity, and selectivity to the specific 1,3-dicaprin of 70% of total products. An adequate selection of the reaction conditions is necessary not only to maximize the conversion of capric acid, but also to minimize the acyl migration reaction and the generation of undesired products. Evidence of kinetically controlled enzymatic acyl migration from sn-3/sn-1 to sn-2 is presented.