82958-27-8

Upstream product

• 68-12-2 N,N-dimethyl-formamide 
• 123-54-6 acetylacetone 
• 217813-03-1 3-methoxy-2-(trimethylsilyl)phenyl-trifluoromethanesulfonate 
• 61227-57-4 7-methoxy-2-methylindan-1-one 
• 2177-70-0 phenyl methacrylate 
• 52685-56-0 7-Hydroxy-2-methyl-1-indanon 
• 81782-33-4 1-(2-Acetyl-3-hydroxyphenyl)-2-propanon 
• 77-78-1 dimethyl sulfate 
• 99678-04-3 4-Methoxy-2,3-dimethylinden 
• 99678-01-0 4-hydroxy-2-methyl-2,3-dihydro-1H-inden-1-one 
• 99678-13-4 (1SR,3RS)-3,4-Dihydro-8-methoxy-1,3-dimethyl-1H-1,3-epidioxy-2-benzopyran 

Downstream Products

• 109463-56-1 Benzyl-(8-methoxy-3-methyl-naphthalen-1-yl)-amine 
• 109463-53-8 2-Benzyl-8-methoxy-1,3-dimethyl-isoquinolinium; bromide 
• 92264-17-0 (1S,3R)-2-Benzyl-8-methoxy-1,3-dimethyl-1,2,3,4-tetrahydro-isoquinoline 
• 92264-17-0 (1S,3S)-2-Benzyl-8-methoxy-1,3-dimethyl-1,2,3,4-tetrahydro-isoquinoline 
• 82958-24-5 1-Amino-8-methoxy-3-methylnaphthalin 
• 73481-00-2 8-Methoxy-1,3-dimethylisochinolin 

Relevant academic research and scientific papers

A multicomponent coupling reaction induced by insertion of arynes into the C=O bond of formamide

And aryne makes three: The three-component coupling of arynes, DMF, and active methylenes has provided an efficient method for the synthesis of 2H-chromene and coumarin derivatives (see scheme). The sequential multistep reactions are driven by the release of strain energy in the arynes and intermediates, and this finding was supported by thermodynamics. Copyright

Acetogenin Isoquinoline Alkaloids, 7. - Simple Syntheses of Useful Diketo Building Blocks for Biomimetic Isoquinoline and Naphthalene Syntheses

For aromatic diketones of the structure 1, which are considered as potential biogenetic precursors of acetogenin isoquinoline alkaloids and thus are required as building blocks for their biomimetic syntheses, two efficient non-biomimetic synthetic ways ar