82992-44-7

Upstream product

• 82992-43-6 (S)-2-Benzyloxymethoxy-4-(triphenyl-λ⁵-phosphanylidene)-pentan-3-one 
• 123-38-6 propionaldehyde 
• 3587-60-8 Benzyloxymethyl chloride 

Downstream Products

• 166957-04-6 (E)-(2S,3R)-2-Benzyloxymethoxy-4-methyl-3-phenyl-hept-4-en-3-ol 
• 82992-46-9 (E)-(2S,3R)-2-Benzyloxymethoxy-4-methyl-hept-4-en-3-ol 
• 82992-47-0 (E)-(2S,3S)-2-Benzyloxymethoxy-4-methyl-hept-4-en-3-ol 

Relevant academic research and scientific papers

Highly Stereoselective Synthesis of Tetrasubstituted Alkenes via -Wittig Rearrangement

A highly stereoselective synthesis of tetrasubstituted alkenes via the sequence Horner-Wadsworth-Emmons-, Grignard- and -Wittig reaction is described, eight examples are given. - Keywords: 2,3-Wittig rearrangement, Claisen rearrangement, Horner-Wadsworth-Emmons reaction, tetrasubstituted alkenes.

HIGHLY STEREOCONTROLLED REDUCTION OF α'-ALKOXYENONES TO GIVE EITHER THE THREO OR ERYTHRO ALLYLIC 1,2-DIOL. ASSIGNMENT OF THE THREO CONFIGURATION TO THE C-15,C-16 DIOL OF PUMILIOTOXIN B.

Model studies indicate that the allylic diol of pumiliotoxin B has the threo configuration, and that this functionality can be prepared with excellent stereocontrol by reduction of an α'-t-butyldiphenylsilyloxyenone.