830-52-4

Basic information

• Product Name: Acetamide, 2-chloro-N-(2,6-dimethylphenyl)-N-methyl-
• CAS NO: 830-52-4
• Molecular Formula: C11H14ClNO
• Molecular Weight: 211.691
• Mol File: 830-52-4.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Acetamide, 2-chloro-N-(2,6-dimethylphenyl)-N-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, 2-chloro-N-(2,6-dimethylphenyl)-N-methyl-(830-52-4)
• EPA Substance Registry System: Acetamide, 2-chloro-N-(2,6-dimethylphenyl)-N-methyl-(830-52-4)

Safety Data

• Hazardous Substances Data: 830-52-4(Hazardous Substances Data)

Upstream product

• 60-29-7 diethyl ether 
• 77-78-1 dimethyl sulfate 
• 1131-01-7 2-chloro-N-(2,6-dimethylphenyl)acetamide 
• 767-71-5 N-methyl-2,6-dimethylaniline 
• 79-04-9 chloroacetyl chloride 

Downstream Products

• 110700-09-9 <<(2,6-Dimethylphenyl)methylcarbamoyl>methyl>triphenylphosphonium-chlorid 
• 53984-94-4 2-amino-N-methyl-2',6'-acetoxylidide 
• 110700-15-7 N-(2,6-Dimethylphenyl)-N-methyl-2,3-butadienamid 
• 121525-46-0 N-(2,6-Dimethylphenyl)-3--4-(diphenylmethylen)-N-methyl-2,2-diphenylcyclobutancarboxamid 
• 121525-45-9 N-(2,6-Dimethylphenyl)-N-methyl-4,4-diphenyl-2,3-butadienamid 
• 110700-12-4 N-(2,6-Dimethylphenyl)-N-methyl-2-(triphenylphosphoranyliden)acetamid 

Relevant articles and documents

Preparation method of 2, 6-dimethylaniline long-chain compound

The invention discloses a preparation method of a 2, 6-dimethylaniline long-chain compound. The method comprises S1, mixing a compound II and a compound III with a first solvent, and adding in a firstbase catalyst for reaction at 0-80 DEG C to obtain a compound IV; S2, uniformly mixing the compound IV prepared in S1, a compound V and a second solvent for mixed reaction at 70-120 DEG C, washing reaction products through ethyl acetate, and filtering out precipitates, namely a compound VI; S3, mixing the compound VI prepared in S2, a second base catalyst, a reactant A, alcohols and a third solvent for mixed reaction at 30-80 DEG C to obtain a compound I, wherein the reactant A is an acyl chloride or ester compound. According to the preparation method of the 2, 6-dimethylaniline long-chain compound, the applied raw materials are all common chemical materials and accordingly are wide in resource and low in prices, products of every reaction save complicated column chromatography and can berecrystallized into high-purity products, so that the preparation method of the 2, 6-dimethylaniline long-chain compound has an industrial scaled synthesis prospect.

Cycloadditions, 12. - Influence of Aromatic Alkyl Groups on the Intramolecular Diels-Alder Reaction of Aryl Allenecarboxylates and of Allenecarboxanilides

The aryl allenecarboxylates 4a-o and the allenecarboxanilides 9a, b, e, h, and l, which differ from one another only by the number or by the size of the alkyl groups attached to the arene, are synthesized by the ylide method via the appropriately substituted 2-halo-, 2-phosphonio-, and 2-phosphoranylideneacetic acid derivatives (1-->2-->3-->4 and 6-->7-->8-->9, resp.).By refluxing in xylene they are transformed into the tricyclic compounds 5 and 10; the rates and their differences are discussed.

BENZODIOXANYL-HYDROXYETHYLENEAMINO-PIPERIDINYL ACETANILIDES, KETONES, ESTERS AND CARBAMATES WHICH EFFECT IMMUNITY AND CALCIUM ENTRY AND BETA-BLOCKADE

Novel compounds of the general formula: STR1 and the pharmaceutically acceptable acid addition salts thereof, wherein: R 1, R 2, R 3 and R 4 are each independently hydrogen, lower alkyl, lower alkoxy, trifluoromethyl, halo, lower alkylthio, lower alkyl sulfinyl or lower alkyl sulfonyl;R 5 is hydrogen or lower alkyl;m is 0 or 1;W is alkylene,--CH=CH--,--O--, or--N(R 6)--, where R 6 is lower alkyl or hydrogen;n is 0 or 1; andQ is lower alkyl, cycloalkyl or optionally substituted phenyl. These compounds combine β-blockade and calcium entry blockade properties in the same compound and therefore are useful in therapy in the treatment of cardiovascular diseases, including myocardial infarction, hypertension, arrhythmia and variant and exercise induced angina. The compounds are also useful in immunosuppressant therapy for immune diseases, such as rheumatoid arthritis.