83019-91-4

Basic information

• Product Name: 1-AMINO-2-(2-NITROBENZENESULFONAMIDO)ETHANE
• Synonyms: N-(2-AMINOETHYL)-2-NITROBENZENESULFONAMIDE;N-(2-NITROBENZENESULFONYL)ETHYLENEDIAMINE;1-AMINO-2-(2-NITROBENZENESULFONAMIDO)ETHANE
• CAS NO: 83019-91-4
• Molecular Formula: C₈H₁₁N₃O₄S
• Molecular Weight: 245.26
• Product Categories: N-(o-Ns)-diaminoalkanes;Monoprotected Diaminoalkanes
• Mol File: 83019-91-4.mol
• Article Data: 5

Chemical Properties

• Melting Point: 164 °C
• Boiling Point: 440.587°C at 760 mmHg
• Flash Point: 220.259°C
• Appearance: /
• Density: 1.425g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.591
• PKA: 8.03±0.40(Predicted)
• CAS DataBase Reference: 1-AMINO-2-(2-NITROBENZENESULFONAMIDO)ETHANE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-AMINO-2-(2-NITROBENZENESULFONAMIDO)ETHANE(83019-91-4)
• EPA Substance Registry System: 1-AMINO-2-(2-NITROBENZENESULFONAMIDO)ETHANE(83019-91-4)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36
• Hazardous Substances Data: 83019-91-4(Hazardous Substances Data)

Usage

Type of compound

Organic compound

Contains

a. Amino group
b. Nitrobenzenesulfonamido group

Potential uses

a. Pharmaceuticals
b. Development of new materials
c. Development of new chemical processes

Possible applications

a. Medicine
b. Agriculture
c. Industry

Research status

Further research needed to fully understand properties and potential uses.

InChI:InChI=1/C8H11N3O4S/c9-5-6-10-16(14,15)8-4-2-1-3-7(8)11(12)13/h1-4,10H,5-6,9H2

Upstream product

• 1694-92-4 2-Nitrobenzenesulfonyl chloride 
• 107-15-3 ethylenediamine 

Downstream Products

• 56202-91-6 N-[2-(2-Hydroxy-2-phenyl-ethylamino)-ethyl]-2-nitro-benzenesulfonamide 
• 1429060-11-6 tert-butyl 4-(methylsulfonyl)-3,4-dihydropyrazine-1(2H)-carboxylate 
• 214000-16-5 N-(tert-butoxycarbonyl)-N'-(2-nitrobenzenesulfonyl)ethylenediamine 
• 844491-03-8 tert-butyl [2-(2-nitrophenylsulfonylamino)ethylamino]acetate 
• 851219-16-4 N¹-cholesteryloxycarbonyl-1-amino-2''-nitrobenzenesulfonamidoethane 
• 1190897-04-1 N₂-{2-[1,3-dihydro-2H-isoindol-2-yl(methyl)amino]-2-oxoethyl}-N₂-(3,5-dimethyl-1,2-benzisoxazol-6-yl)-N₁-[2-{[(2-nitrophenyl)sulfonyl]amino}ethyl]glycinamide 
• 1346812-03-0 1-(2-nitrophenylsulfonyl)imidazolidine-2-thione 
• 529509-40-8 C₃₂H₃₀FN₉O₅S 
• 529509-37-3 1-(2-Nitro-benzenesulfonyl)-(6S)-[1,4]diazepan-6-ol 
• 529509-36-2 N-[2-({2S}-3-chloro-2-hydroxy-propylamino)-ethyl]-2-nitro-benzenesulfonamide 
• 53671-35-5 N-[2-(2-Hydroxy-3-phenoxy-propylamino)-ethyl]-2-nitro-benzenesulfonamide 

Relevant articles and documents

tBu4octapa-alkyl-NHS for metalloradiopeptide preparation

The peptide is an important class of biological targeting molecule; herein, a new bifunctional octadentate non-macrocyclic H4octapa,tBu4octapa-alkyl-NHS, which is compatible with solid-phase peptide synthesis and thus usef

A DNA-Encoded Chemical Library Incorporating Elements of Natural Macrocycles

Here we show a seven-step chemical synthesis of a DNA-encoded macrocycle library (DEML) on DNA. Inspired by polyketide and mixed peptide-polyketide natural products, the library was designed to incorporate rich backbone diversity. Achieving this diversity, however, comes at the cost of the custom synthesis of bifunctional building block libraries. This study outlines the importance of careful retrosynthetic design in DNA-encoded libraries, while revealing areas where new DNA synthetic methods are needed.

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