83026-98-6Relevant academic research and scientific papers
Identification of compounds that inhibit replication of human immunodeficiency virus
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, (2008/06/13)
The present invention relates to the discovery of a novel class of compounds that inhibit the replication of human immunodeficiency virus (HIV) and approaches to identify these compounds. More specifically, it has been found that enzymatically prepared al
Preparation of protected α-alkoxyglycines
Kawai, Masao,Hosoda, Kouji,Omori, Yoshimasa,Yamada, Keiichi,Hayakawa, Shoko,Yamamura, Hatsuo,Butsugan, Yasuo
, p. 1545 - 1554 (2007/10/03)
N-Carbobenzoxy-α-alkoxyglycine esters were synthesized by H2SO4-catalyzed O-alkylation of N-carbobenzoxy-α-hydroxyglycine and also by base treatment of N-carbobenzoxy-N-chloroglycine methyl ester in the corresponding alcohol. Saponification of the protected α-alkoxyglycines gave free acids which can be used for the synthesis of α-alkoxyglycine residue-containing peptides.
