830331-51-6Relevant articles and documents
Design, synthesis, and biological activity of novel, potent, and selective (benzoylaminomethyl)thiophene sulfonamide inhibitors of c-Jun-N-terminal kinase
Rückle, Thomas,Biamonte, Marco,Grippi-Vallotton, Tania,Arkinstall, Steve,Cambet, Yves,Camps, Montserrat,Chabert, Christian,Church, Dennis J.,Halazy, Serge,Jiang, Xuliang,Martinou, Isabelle,Nichols, Anthony,Sauer, Wolfgang,Gotteland, Jean-Pierre
, p. 6921 - 6934 (2007/10/03)
Several lines of evidence support the hypothesis that c-Jun N-terminal kinases (JNKs) play a critical role in a wide range of disease states including cell death (apoptosis)-related and inflammatory disorders (epilepsy, brain, heart and renal ischemia, ne