83051-34-7Relevant academic research and scientific papers
External oxidant-free dehydrogenative lactonization of 2-arylbenzoic acids via visible-light photocatalysis
Shao, Ailong,Zhan, Jirui,Li, Na,Chiang, Chien-Wei,Lei, Aiwen
, p. 3582 - 3589 (2018/04/14)
An external oxidant-free C-H functionalization/C-O bond formation reaction for constructing benzo-3,4-coumarins accompanied by quantitative H2 evolution has been developed. High functional group tolerance and excellent reaction efficiency are s
Microwave-assisted cyclization under mildly basic conditions: Synthesis of 6 h -benzo [c] chromen-6-ones and their 7,8,9,10-tetrahydro analogues
Dao, Pham Duy Quang,Ho, Son Long,Lim, Ho-Jin,Cho, Chan Sik
, p. 4140 - 4146 (2018/04/14)
Aryl 2-bromobenzoates and aryl 2-bromocyclohex-1-enecarboxylates are cyclized by microwave irradiation in dimethylformamide in the presence of K2CO3 to give the corresponding 6H-benzo[c]chromen-6-ones and their 7,8,9,10-tetrahydro analogues, respectively, in 50-72% yields. Aryl 3-bromoacrylates are also converted into 2H-chromen-2-ones under the employed conditions.
Skeletal diversity construction via a branching synthetic strategy
Wyatt, Emma E.,Fergus, Suzanne,Galloway, Warren R. J. D.,Bender, Andreas,Fox, David J.,Plowright, Alleyn T.,Jessiman, Alan S.,Welch, Martin,Spring, David R.
, p. 3296 - 3298 (2008/09/19)
A branching synthetic strategy was used to efficiently generate structurally diverse scaffolds, which span a broad area of chemical descriptor space, and their biological activity against MRSA was demonstrated. The Royal Society of Chemistry 2006.
(1-Benzylindole-3-yl)alkanoic acids; novel nonsteroidal inhibitors of steroid 5α-reductase (I)
Sawada, Kozo,Hirai, Hideo,Golden, Patrick,Okada, Satoshi,Sawada, Yuki,Hashimoto, Masashi,Tanaka, Hirokazu
, p. 1683 - 1687 (2007/10/03)
A novel series of indole-3-alkanoic acids with varied N-benzyl substituents were synthesized as nonsteroidal inhibitors of steroid 5α- reductase. The structure-activity relationships in this series were studied and the optimum carboxylic acid side chain w
