83073-99-8

Upstream product

• 75-15-0 carbon disulfide 
• 121-44-8 triethylamine 
• 100-61-8 N-methylaniline 

Downstream Products

• 114324-54-8 N,N'-dimethyl-N,N'-diphenylthiuram sulfide 
• 2740-95-6 1,3-dimethyl-1-phenyl-thiourea 
• 202214-23-1 [Rh(N-methyl,N-phenyl-dithiocarbamate)(norbornadiene)] 
• 202214-22-0 [Rh(N-methyl,N-phenyl-dithiocarbamate)(1,5-cyclooctadiene)] 
• 202214-29-7 [Rh2(μ-N-methyl,N-phenyl-dithiocarbamate)(1,5-cyclooctadiene)(CO)2]BF4 
• 202214-25-3 [Rh₂(N-methyl,N-phenyl-dithiocarbamate)2(CO)2(norbornadiene)] 
• 202214-24-2 [Rh(N-methyl,N-phenyl-dithiocarbamate)(CO)2] 
• 192883-92-4 (4R,5S,6S)-6-((R)-1-Hydroxy-ethyl)-4-methyl-3-(methyl-phenyl-thiocarbamoylsulfanyl)-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester 

Relevant academic research and scientific papers

Novel dithiocarbamate carbapenems with anti-MRSA activity

A new series of 1β-methyl carbapenems, in which a disubstituted-aminothiocarbonylthio moiety was attached to the C-2 position of the carbapenem nucleus, were prepared and evaluated for anti-MRSA activity. These derivatives showed good in vitro antibacterial activity against high-level MRSA, and the finding of good affinity for PBP-2' supported these results. Some of the compounds having favorable protein-binding affinity showed excellent in vivo anti-MRSA activity. Copyright (C) 1998 Elsevier Science Ltd.

Activation of Dithiocarbamate by 2-Halothiazolium Salts

Activation of dithiocarbamate salts with 2-halo-3-alkyl-4-phenylthiazolium salt and subsequent one-pot nucleophilic reaction with N, S, and O nucleophiles provided substituted thioureas, dithiocarbamates, and thiocarbamates or amides, respectively, under very mild conditions.A useful thiocarbonyl-transfer reaction is also described that consists of activation of imidazolodithiocarbamate and a subsequent one-pot nucleophilic reaction. (Thiocarbonyl)diimidazole is generated in situ.