83081-99-6

Upstream product

• 847924-83-8 2-[2-(3-benzoylpyridin-2-yl)ethyl]-1H-isoindole-1,3(2H)-dione 
• 847924-79-2 2-[(3Z)-3-hydroxy-5-oxo-5-phenylpent-3-en-1-yl]-1H-isoindole-1,3(2H)-dione 
• 847924-81-6 2-[(3Z)-3-amino-5-oxo-5-phenylpent-3-en-1-yl]-1H-isoindole-1,3(2H)-dione 
• 3339-73-9 3-phthalimidopropanoic acid 
• 847924-85-0 5-phenyl-7,8-dihydro-1,6-naphthyridine 

Relevant academic research and scientific papers

Synthesis of 5-phenyl-5,6,7,8-tetrahydro-1,6-naphthyridines and 5-phenyl-6,7,8,9-tetrahydro-5H-pyrido[3,2-c]azepines as potential D1 receptor ligands

A new access to 5-phenyl-5,6,7,8-tetrahydro-1,6-naphthyridines 25a-28a (n=1) and 5-phenyl-6,7,8,9-tetrahydro-5H-pyrido[3,2-c]azepines 25b-28b (n=2) has been developed by first preparing the functional pyridine moiety followed by intramolecular cyclization forming the partially reduced ring.