83121-15-7

Basic information

• Product Name: 2,4-Difluoro-3,5-dichloroaniline
• Synonyms: 2,4-DIFLUORO-3,5-DICHLORO ANILINE;3,5-DICHLORO-2,4-DIFLUOROANILINE;2,4-DIFLUORO-3,5-DICHLORANILINE;2,4-DICHLORO-3,5-DIFLUOROANILINE;E-14;2,4-Difluoro-3,5-dic;1-Amino-3,5-dichloro-2,4-difluorobenzene;3,5-Dichloro-2,4-Difluoro-BenzenaMine
• CAS NO: 83121-15-7
• Molecular Formula: C₆H₃Cl₂F₂N
• Molecular Weight: 197.9975264
• Mol File: 83121-15-7.mol
• Article Data: 2

Chemical Properties

• Melting Point: 75 °C
• Boiling Point: 268.1 °C at 760 mmHg
• Flash Point: 116 °C
• Appearance: /
• Density: 1.596 g/cm³
• Vapor Pressure: 0.00784mmHg at 25°C
• Refractive Index: 1.562
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility: soluble in Methanol
• PKA: 1.15±0.10(Predicted)
• CAS DataBase Reference: 2,4-Difluoro-3,5-dichloroaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Difluoro-3,5-dichloroaniline(83121-15-7)
• EPA Substance Registry System: 2,4-Difluoro-3,5-dichloroaniline(83121-15-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 83121-15-7(Hazardous Substances Data)

Usage

Chemical Properties

White powder

InChI:InChI=1/C6H3Cl2F2N/c7-2-1-3(11)6(10)4(8)5(2)9/h1H,11H2

Upstream product

• 5580-79-0 2,3,4,5-tetrafluoro-1-nitrobenzene 
• 15952-70-2 2,4-difluoro-3,5-dichloro-nitrobenzene 
• 87-61-6 1,2,3-trichlorobenzene 
• 17700-09-3 4-nitro-1,2,3-trichlorobenzene 
• 634-67-3 2,3,4-trichloroaniline 
• 634-66-2 1,2,3,4,-tetrachlorobenzene 

Downstream Products

• 118159-53-8 4-Hydroxy-3,5-dichloro-2-fluoroaniline 
• 13656-49-0 1,3,5-trichloro-2,4-difluorobenzene 
• 83121-16-8 3,5-dichloro-2,4-difluoro-phenyl-isocyanate 
• 83121-18-0 teflubenzuron 
• 1417340-63-6 1-(3,5-dichloro-2,4-difluorophenyl)-3-[(4-methyl-1,2,3-thiadiazol-5-yl)carbonyl]urea 
• 15952-70-2 2,4-difluoro-3,5-dichloro-nitrobenzene 
• 1437779-57-1 5-(5-(3,5-dichloro-2,4-difluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-3,3-dimethylbenzo[c][1,2]oxaborol-1(3H)-ol 
• 1437779-98-0 2-(3,5-dichloro-2,4-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 1437779-97-9 1-bromo-3,5-dichloro-2,4-difluorobenzene 
• 1365074-88-9 N-{4-[3-(3,5-dichloro-2,4-difluorophenyl)-2-hydroxy-3-(trifluoromethyl)pyrrolidin-1-yl]-2-(trifluoromethyl)benzyl}propanamide 
• 1365449-83-7 4-[3-(3,5-dichloro-2,4-difluorophenyl)-2-hydroxy-3-(trifluoromethyl)pyrrolidin-1-yl]-2-(trifluoromethyl)benzonitrile 
• 1364674-16-7 4-[3-(3,5-dichloro-2,4-difluorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]-2-(trifluoromethyl)benzonitrile 
• 1364674-15-6 3-(3,5-dichloro-2,4-difluorophenyl)-3-(trifluoromethyl)pyrrolidine 
• 1364674-14-5 1-benzyl-3-(3,5-dichloro-2,4-difluorophenyl)-3-(trifluoromethyl)pyrrolidine 

Relevant articles and documents

Preparation method for 3,5,-dichloro-2,4,-difluoroaniline

The invention relates to the field of organic synthesis, specifically to a preparation method for 3,5,-dichloro-2,4,-difluoroaniline and application thereof. The preparation method for 3,5,-dichloro-2,4,-difluoroaniline provided by the invention comprises the following steps: 1) nitration reaction; 2) reduction reaction; 3) diazotization reaction; 4) nitration reaction; 5) fluorination reaction; and 6) reduction reaction. The preparation method for 3,5,-dichloro-2,4,-difluoroaniline provided by the invention has the following beneficial effects: 1) the method has mild reaction conditions, is stable and controllable, has less active sites, is insusceptible to side reaction, and has good yield and quality in the whole line; and 2) raw materials are cheap and easily available, so cost can be effectively reduced, and energy is saved; meanwhile, the use of chlorine gas is avoided, so the method is environment-friendly.