831215-57-7Relevant academic research and scientific papers
Chiral phosphine oxide BINAPO as a Lewis base catalyst for asymmetric allylation and aldol reaction of trichlorosilyl compounds
Kotani, Shunsuke,Hashimoto, Shunichi,Nakajima, Makoto
, p. 3122 - 3132 (2007/10/03)
Chiral phosphine oxide BINAPO, which was readily prepared from chiral phosphine BINAP, exhibited good catalytic activities in the reaction of trichlorosilyl compounds via hypervalent silicate intermediates. The allylation of aldehydes with allyltrichloros
Chiral phosphine oxide BINAPO as a catalyst for enantioselective allylation of aldehydes with allyltrichlorosilanes
Nakajima, Makoto,Kotani, Shunsuke,Ishizuka, Tadao,Hashimoto, Shunichi
, p. 157 - 159 (2007/10/03)
The effectiveness of chiral phosphine oxide BINAPO as a catalyst for the enantioselective addition of allyltrichlorosilanes to aldehydes was demonstrated, wherein the combination of diisopropylethylamine and tetrabutylammonium iodide as additives is cruci
One-pot enantioselective synthesis of optically active homoallylic alcohols from allyl halides
Nakajima, Makoto,Saito, Makoto,Hashimoto, Shunichi
, p. 306 - 307 (2007/10/03)
A one-pot, convenient method for the preparation of optically active homoallylic alcohols from allyl halides was developed. Allyltrichlorosilanes were generated in situ from allyl halides and trichlorosilane in the presence of cuprous chloride and tertiary amine. Without isolation of the allyltrichlorosilanes, benzaldehyde and chiral biquinoline N,N'-dioxide were introduced into the same flask, producing the corresponding homoallylic alcohols with good to high enantioselectivities.
