83124-72-5Relevant articles and documents
Enol Ethers, VIII. Acylation of Enol Ethers with Reactive Carbonyl Chlorides
Effenberger, Franz,Maier, Roland,Schoenwaelder, Karl-Heinz,Ziegler, Thomas
, p. 2766 - 2782 (2007/10/02)
Enol ethers 2 are acylated under mild conditions with activated acyl chlorides, e. g. chloroacetyl chlorides 1a, b, cyanoacetyl chloride (6c), and malonic acid chlorides 6a, b in good yields.The products formed and the yield depend on the acylation potential of the acyl chlorides.The potential β-keto aldehydes 4, 5, and 1,3,5-tricarbonyl compounds 8 obtained are valuable intermediates for heterocyclic synthesis.