83170-00-7

Upstream product

• 3764-01-0 2,4,6-trichloropyrimidine 
• 50-01-1 guanidine hydrochloride 

Downstream Products

• 84097-23-4 4-benzylamino-6-chloro-2-guanidinopyrimidine hydrochloride 
• 93871-78-4 2-amino-4,6-di(benzylamino)pyrimidine 

Relevant academic research and scientific papers

Investigations of Pt(II) coordination compounds with substituted guanidinopyrimidines

Some new chelates of platinum(II) with substituted guanidinopyrimidines have been prepared and characterized. On the basis of IR and UV-VIS spectra, the structure of the nearest environment of the central ion of these chelates has been characterized and the most likely structures of the obtained coordination compounds were proposed. In each chelate the square-planar coordination sphere of the Pt(II) ion is formed by the guanidinopyrimidine molecule and the halide ligand. Guanidinopyrimidine is the mono- or bidentate ligand binding through the nitrogen atoms of the guanidine group. Halides play a role of terminal and bridging ligands as well.

Preparation and Spectroscopic Investigation of Pd(II) Chelates with Substituted Guanidinopyrimidines

Some new chelates of palladium(II) with substituted guanidinopyrimidines have been prepared and characterized.On the basis of IR and UV-VIS spectra, the structure of the nearest environment of the central ion of these chelates has been characterized.Their ligands are bonded with metal ion via nitrogen atoms of the guanidine group. - Key words: complex compounds; synthesis; IR; VIS-spectra; magnetic susceptibilities

COORDINATION COMPOUNDS OF COPPER(II) WITH SUBSTITUTED GUANIDINOPYRIMIDINES

Some complexes of copper(II) with 4,6-dichloro-2-guanidinopyrimidine and 2,6-dichloro-4-guanidinopyrimidine have been prepared and characterized.On the basis of vibrational and electronic spectroscopy, magnetism and elemental analysis the structures of these chelates were identified.Thermal behavior of these complexes has also been studied.Substituted guanidinopyrimidines behave as bidentate ligands and are bonded via the N-atom of pyrimidine ring and N-atom of guanidine group with metal ion.

Synthesis of Some Substituted Guanidinopyrimidines and their Structural Assignment by 13C and 1H NMR

A series of substituted 2- and 4-guanidinopyrimidines were prepared by reaction of halopyrimidines with guanidine; alkylamino and amino substituents were introduced by subsequent halogen replacement by primary amines or ammonia or the catalytic reduction of nitro groups.Structural assignments were made on the basis of 13C and 1H nmr.A guanidinopteridine and a bispyrimidinylguanidine were also synthesized.Some unsuccessful reaction illustrated the low nucleophilic reactivity and thermal instability of the guanidine group.