83170-03-0Relevant articles and documents
Coordination Compounds of Copper(II) with Aminoguanidinopyrimidines
Zawadzki, H. J.
, p. 1293 - 1302 (2007/10/02)
Some new chelates of copper(II) with substituted guanidinopyrimidines have been obtained and characterized. On the basis of IR and VIS spectra the structure of the nearest environment of the central ion in these chelates has been determined. These ligands are bonded with metal ion via the nitrogens atoms of pyrimidine heterocyclic ring and guanidine group. Key words: complexes, synthesis, IR-spectra
Synthesis of Some Substituted Guanidinopyrimidines and their Structural Assignment by 13C and 1H NMR
Ladd, David L.
, p. 917 - 921 (2007/10/02)
A series of substituted 2- and 4-guanidinopyrimidines were prepared by reaction of halopyrimidines with guanidine; alkylamino and amino substituents were introduced by subsequent halogen replacement by primary amines or ammonia or the catalytic reduction of nitro groups.Structural assignments were made on the basis of 13C and 1H nmr.A guanidinopteridine and a bispyrimidinylguanidine were also synthesized.Some unsuccessful reaction illustrated the low nucleophilic reactivity and thermal instability of the guanidine group.
Guanidinopyrimidine compounds, compositions and method of using as a diuretic
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, (2008/06/13)
2,4-Amino, guanidinopyrimidines have diuretic activity. A representative species of these compounds is 2-guanidino-4-amino-6-chloroguanidine which is prepared by the stepwise replacement of first the 2-halo of a 2,4,6-trihalopyrimidine by guanidino and then the 4-halo by ammonia.
