83194-70-1Relevant academic research and scientific papers
Facile Synthesis of Halogen Decorated para -/ meta -Hydroxybenzoates by Iridium-Catalyzed Borylation and Oxidation
Shahzadi, Tayyaba,Saleem, Rahman S. Z.,Chotana, Ghayoor A.
, p. 4336 - 4342 (2018/11/23)
Hydroxybenzoates are an important class of phenols that are widely used as preservatives and antiseptics in the food and pharmaceutical industries. In this report, a facile preparation of 2,6- and 2,3-disubstituted 4/5-hydroxybenzoates by iridium-catalyze
COMPOUNDS AND METHODS FOR REGULATING INSULIN SECRETION
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Page/Page column 119; 120, (2018/10/19)
Disclosed herein are methods for inducing insulin secretion in a glucose-dependent manner and compounds for use in these methods.
METHOD OF MANUFACTURING 4-HYDROXY-2-METHYLBENZOIC ACID DERIVATIVE
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Paragraph 0049, (2016/11/17)
PROBLEM TO BE SOLVED: To provide a method for manufacturing 4-hydroxy-2-methylbenzoic esters simply in a short time. SOLUTION: There is provided a method for manufacturing a 4-hydroxy-2-methylbenzoic acid derivative (1) by air oxidizing a 2-methyl-4-oxo-2
Copper(II)-catalyzed aromatization followed by bromination of cyclohexenones leading to phenols and bromophenols
Tong, Hung-Chun,Reddy, K. Rajender,Liu, Shiuh-Tzung
, p. 3256 - 3261 (2014/06/09)
Conversion of substituted cyclohexenones into the corresponding phenols can be achieved using copper acetate as the catalyst in the presence of LiBr and CF3COOH under oxygen. With the use of excess LiBr, electrophilic aromatic bromination afforded the corresponding bromophenol under similar catalytic conditions. Copyright
The use of Hagemann's Esters to prepare highly functionalized phenols and benzenes
Majetich, George,Allen, Scott
, p. 104 - 124 (2012/11/07)
Hagemann's esters can be converted into highly functionalized phenols or arenes. The systematic functionalization of Hagemann's ester derivatives permits the preparation of tri-and tetraalkyl-substituted phenols or tetra-, penta-, and hexaalkyl-substituted benzenes. Kotnis's aromatization procedure was found to be solvent dependent, and Suzuki couplings were found to be sensitive to steric hindrance. Wittig olefination and ortho-Claisen reactions were reliable means to introduce alkyl substituents at C-4 and/or C-5 positions, respectively. The acid-promoted dehydration of tertiary alcohol 46 to produce enone 47, followed by its selective alkylation (cf. 48) is new. ARKAT USA, Inc.
PIPERAZINE DERIVATIVES USEFUL AS CCR5 ANTAGONISTS
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Page/Page column 27, (2010/02/12)
The use is described of CCR5 antagonists of formula (I) or a pharmaceutically acceptable salt thereof, wherein: R is optionally substituted phenyl, pyridyl, thiophenyl or naphthyl; R 1 is hydrogen or alkyl; R 2 is substituted phenyl, substituted heteroary
Piperazine derivatives useful as CCR5 antagonists
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Page column 41, (2010/02/05)
The use of CCR5 antagonists of the formula or a pharmaceutically acceptable salt thereof, wherein R is optionally substituted phenyl, pyridyl, thiophenyl or naphthyl; R1is hydrogen or alkyl; R2is substituted phenyl, substituted heter
PREPARATION AND CYCLOADDITION OF FUNCTIONALIZED 4,6-DIALKYLPYRONE-5-CARBOXYLATES. SYNTHESIS OF BICYCLIC LACTONES AND SUBSTITUTED BENZOATES
Jung, Michael E.,Hagenah, Jeffrey A.
, p. 117 - 121 (2007/10/02)
Several alkyl pyrone-5-carboxylates (coumalates) with alkyl and functionalized alkyl substituents at C4 and C6 have been prepared by a general route; their cycloadditions with electron-rich olefins have been carried out to provide aromatic and non-aromati
