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(5-Amino-1,2-dihydro-1-methyl-3-phenylpyrido[3,4-b]pyrazin-7-yl)carbamic acid ethyl ester, also known as PNU-102035, is a chemical compound that serves as a selective adenosine A1 receptor antagonist. It is recognized for its potent and selective action on the adenosine A1 receptor, which has led to its use in various research and therapeutic applications. PNU-102035 has demonstrated neuroprotective effects in animal studies and holds promise for the treatment of neurodegenerative diseases.

83269-12-9

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83269-12-9 Usage

Uses

Used in Pharmaceutical Research:
PNU-102035 is used as a pharmacological tool for studying the adenosine A1 receptor and its role in physiological processes. This application aids in understanding the receptor's function and its potential as a therapeutic target for various conditions.
Used in Neurodegenerative Disease Treatment:
In the medical field, (5-Amino-1,2-dihydro-1-methyl-3-phenylpyrido[3,4-b]pyrazin-7-yl)carbamic acid ethyl ester is used as a potential therapeutic agent for the treatment of neurodegenerative diseases. Its neuroprotective properties make it a candidate for conditions such as Alzheimer's, Parkinson's, and other related disorders.
Used in Chronic Pain Management:
PNU-102035 is being investigated for its potential use in managing chronic pain. As an adenosine A1 receptor antagonist, it may help in modulating pain signals and providing relief to patients suffering from chronic pain conditions.
Used in Cognitive and Psychiatric Illness Treatment:
(5-Amino-1,2-dihydro-1-methyl-3-phenylpyrido[3,4-b]pyrazin-7-yl)carbamic acid ethyl ester is also being studied for its potential role in treating cognitive disorders and psychiatric illnesses. Its ability to modulate neurotransmitter release could contribute to the development of new treatment strategies for these conditions.
Used in Drug Delivery Systems:
Similar to gallotannin, PNU-102035 may benefit from novel drug delivery systems to enhance its applications and efficacy. These systems could improve the compound's delivery, bioavailability, and therapeutic outcomes in various medical applications.

Check Digit Verification of cas no

The CAS Registry Mumber 83269-12-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,2,6 and 9 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 83269-12:
(7*8)+(6*3)+(5*2)+(4*6)+(3*9)+(2*1)+(1*2)=139
139 % 10 = 9
So 83269-12-9 is a valid CAS Registry Number.
InChI:InChI=1/C17H19N5O2/c1-3-24-17(23)21-14-9-13-15(16(18)20-14)19-12(10-22(13)2)11-7-5-4-6-8-11/h4-9H,3,10H2,1-2H3,(H3,18,20,21,23)

83269-12-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl N-(5-amino-1-methyl-3-phenyl-2H-pyrido[3,4-b]pyrazin-7-yl)carbamate

1.2 Other means of identification

Product number -
Other names N-(5-Amino-1-methyl-3-phenyl(1,2-dihydropyridino[5,4-b]pyrazin-7-yl))ethoxycarboxamide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:83269-12-9 SDS

83269-12-9Downstream Products

83269-12-9Relevant academic research and scientific papers

1,2-Dihydropyrido[3,4-b]pyrazines: Structure-activity relationships

Temple Jr.,Wheeler,Elliott,Rose,Comber,Montgomery

, p. 91 - 95 (2007/10/02)

Certain derivatives containing the 1,2-dihydropyrido[3,4-b]pyrazine (1-deaza-7,8-dihydropteridine) ring system are active against experimental neoplasms in mice. The mechanism of action of these agents has r539w1 =4-amino-1-deaza-7,8-dihydro-6-[(N-methyla

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