83269-15-2Relevant academic research and scientific papers
Potential Antimitotic Agents. Synthesis of Some Ethyl Benzopyrazin-7-ylcarbamates, Ethyl Pyridopyrazin-7-ylcarbamates, and Ethyl Pyrido-as-triazin-7-ylcarbamates
Temple, Carroll,Rener, Gregory A.
, p. 3044 - 3050 (2007/10/02)
Ring analogues and derivatives of the 1,2-dihydropyridopyrazin-7-ylcarbamates (e.g., 29), antimitotic agents with antitumor activity, were prepared in the search for compounds with greater selectivity.Methods were developed for the conversion of su
1,2-Dihydropyrido[3,4-b]pyrazines: Structure-activity relationships
Temple Jr.,Wheeler,Elliott,Rose,Comber,Montgomery
, p. 91 - 95 (2007/10/02)
Certain derivatives containing the 1,2-dihydropyrido[3,4-b]pyrazine (1-deaza-7,8-dihydropteridine) ring system are active against experimental neoplasms in mice. The mechanism of action of these agents has r539w1 =4-amino-1-deaza-7,8-dihydro-6-[(N-methyla
