832738-85-9

Upstream product

• 79-04-9 chloroacetyl chloride 
• 832738-83-7 3-(4-fluoro-benzyl)-2-phenyl-2,3-dihydro-1H-pyrido[2,3-d]pyrimidin-4-one 
• 832738-80-4 3-(4-fluoro-benzyl)-2-phenyl-3H-pyrido[2,3-d]pyrimidin-4-one 
• 23411-09-8 2-phenyl-4H-pyrido[2,3-d][1,3]oxazin-4-one 

Relevant academic research and scientific papers

Synthesis and conformation analysis of 3-substituted derivatives if 1H,3H-pyrido[2,3-d] pyrimidin-4-one of expected depressive nervous system. Part III

Four series of new 1-aryl (heteroaryl) piperazinylacetyl derivatives of 1H,3H-pyrido[2,3-d] pyrimidin-4-one VIIa-o were synthesised. Substrates for the synthesis of VIa-d were obtained from the respective 3H-pyrido[2,3-d])pyrimidines IV a-d in the reaction with NaBH4. Compounds VIa-d were prepared by chloroacetylation. The obtained 1-chloroacetyl derivatives in the reaction with respective aryl (heteroaryl) piperazine formed 1-aminoacetyl derivatives of 2-phenyl-1H,3H-pyrido[2,3-d]pyrimidin-4-one compounds VIIa-n. The structure of compounds was analysed by 1H, 13C NMR spectroscopy.