832741-22-7

Upstream product

• 765292-65-7 ethyl 7-(3-nitrophenyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate 

Downstream Products

• 950733-06-9 ethyl 7-{3-[(3-chlorobenzoyl)amino]phenyl}pyrazolo[1,5-a]pyrimidine-3-carboxylate 
• 950733-16-1 ethyl 7-[3-({[(3-chlorophenyl)amino]carbonyl}amino)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxylate 
• 950737-76-5 ethyl 7-(3-{[4-{[(tert-butoxycarbonyl)(methyl)amino]methyl}-3-(trifluoromethyl)benzoyl]amino}phenyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate 
• 950737-82-3 ethyl 7-(3-{[3-nitro-5-(trifluoromethyl)benzoyl]amino}phenyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate 
• 950732-66-8 ethyl 7-(3-{[4-methoxy-3-(trifluoromethyl)benzoyl]amino}phenyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate 
• 950732-45-3 ethyl 7-{3-[(3-methoxybenzoyl)amino]phenyl}pyrazolo[1,5-a]pyrimidine-3-carboxylate 
• 950733-39-8 ethyl 7-(3-{[4-chloro-3-(trifluoromethyl)benzoyl]amino}phenyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate 
• 950732-63-5 ethyl 7-(3-{[2-chloro-5-(trifluoromethyl)benzoyl]amino}phenyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate 
• 950732-41-9 ethyl 7-{3-[(3-bromobenzoyl)amino]phenyl}pyrazolo[1,5-a]pyrimidine-3-carboxylate 
• 950732-62-4 ethyl 7-(3-{[4-methyl-3-(trifluoromethyl)benzoyl]amino}phenyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate 
• 950733-40-1 ethyl 7-(3-{[2-methyl-5-(trifluoromethyl)benzoyl]amino}phenyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate 
• 950732-38-4 pyrazolo[1,5-a]pyrimidine-3-carboxylic acid 7-[3-[[3-(trifluoromethyl)benzoyl]amino]phenyl] ethyl ester 

Relevant academic research and scientific papers

Identification of pyrazolo[1,5-a]pyrimidine-3-carboxylates as B-Raf kinase inhibitors

B-Raf kinase plays a critical role in the Raf-MEK-ERK signaling pathway and inhibitors of B-Raf could be used in the treatment of melanomas, colorectal cancer, and other Ras related human cancers. We have identified novel small molecule pyrazolo[1,5-a]pyr

Dihydropyrazolo[1,5-A]pyrimidine and dihydroimidazo[1,5-A]pyrimidine derivatives and methods of use thereof

The present invention relates to dihydropyrazolo[1,5-a]pyrimidine and dihydroimidazo[1,5-a]pyrimidine derivatives, compositions comprising an effective amount of a dihydropyrazolo[1,5-a]pyrimidine or a dihydroimidazo[1,5-a]pyrimidine derivative and method

Pyrazolo[1,5-A]pyrimidine derivatives and methods of use thereof

The present invention relates to pyrazolo[1,5-a]pyrimidine derivatives, compositions comprising an effective amount of a pyrazolo[1,5-a]pyrimidine derivative and methods for treating or preventing cancer, comprising administering to a subject in need thereof an effective amount of a pyrazolo[1,5-a]pyrimidine derivative.