832755-13-2

Basic information

• Product Name: 2-Fluoro-4-(methylsulfonyl)aniline
• Synonyms: 2-Fluoro-4-(methylsulfonyl)phenylamine;2-Fluoro-4-(methylsulfonyl)aniline;2-Fluoro-4-(methylsulphonyl)aniline 99%;4-Amino-3-fluorophenyl methyl sulphone;2-fluoro-4-(Methylsulfonyl)benzenaMine;2-fluoro-4-Methanesulfonylaniline;1-Amino-2-fluoro-4-(methylsulphonyl)benzene
• CAS NO: 832755-13-2
• Molecular Formula: C₇H₈FNO₂S
• Molecular Weight: 189.21
• Product Categories: Amines and Anilines;Boron, Nitrile, Thio,& TM-Cpds;Benzene series;API intermediates
• Mol File: 832755-13-2.mol
• Article Data: 6

Chemical Properties

• Melting Point: 145-147°C
• Boiling Point: 370.989 °C at 760 mmHg
• Flash Point: 178.168 °C
• Appearance: /
• Density: 1.374 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.551
• Storage Temp.: 2-8°C(protect from light)
• PKA: -0.04±0.10(Predicted)
• CAS DataBase Reference: 2-Fluoro-4-(methylsulfonyl)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Fluoro-4-(methylsulfonyl)aniline(832755-13-2)
• EPA Substance Registry System: 2-Fluoro-4-(methylsulfonyl)aniline(832755-13-2)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 832755-13-2(Hazardous Substances Data)

Usage

General Description

2-Fluoro-4-(methylsulfonyl)aniline is a chemical compound that is primarily used for research and development purposes in the field of organic chemistry. 2-Fluoro-4-(methylsulfonyl)aniline has a molecular formula of C7H8FNO2S and is characterized by the presence of a fluoro group and a methylsulfonyl group attached to an aniline molecule. It is a brown solid with several commercial applications, particularly in the production of pharmaceuticals and polymers. However, as with many chemicals, it must be handled with care due to potential health and environmental risks, requiring proper storage and disposal procedures.

InChI:InChI=1/C7H8FNO2S/c1-12(10,11)5-2-3-7(9)6(8)4-5/h2-4H,9H2,1H3

Upstream product

• 57946-56-2 2-fluoro-4-chloroaniline 
• 20277-69-4 sodium methansulfinate 
• 29632-74-4 2-fluro-4-iodoaniline 
• 367-24-8 4-bromo-2-fluoroaniline 

Downstream Products

• 1001399-54-7 methyl 1-[2-fluoro-4-(methylsulfonyl)phenyl]-2-oxo-3-pyrrolidinecarboxylate 
• 1424336-84-4 C₂₇H₃₃FN₄O₇S 
• 1424336-86-6 C₂₈H₃₅FN₄O₇S 
• 1424337-00-7 tert-butyl endo-3-(4-(2-fluoro-4-(methylsulfonyl)phenylamino)-6,7-dimethoxyquinazolin-2-ylamino)-8-azabicyclo[3.2.1]octane-8-carboxylate 
• 1424337-02-9 tert-butyl exo-3-((4-(2-fluoro-4-(methylsulfonyl)phenylamino)-6,7-dimethoxyquinazolin-2-ylamino)methyl)-8-azabicyclo[3.2.1]octane-8-carboxylate 
• 1424336-77-5 2-chloro-4-(2-fluoro-4-methylsulfonylphenylamino)-6,7-dimethoxyquinazoline 

Relevant articles and documents

HETEROCYCLIC CARBOXYLIC ACID AMIDE LIGAND AND APPLICATIONS THEREOF IN COPPER CATALYZED COUPLING REACTION OF ARYL HALOGENO SUBSTITUTE

Provided are a heterocyclic carboxylic acid amide ligand and applications thereof in a copper catalyzed coupling reaction. Specifically, provided are uses of a compound represented by formula (I), definitions of radical groups being described in the specifications. The compound represented by formula (I) can be used as the ligand in the copper catalyzed coupling reaction of the aryl halogeno substitute, and is used or catalyzing the coupling reaction for forming the aryl halogeno substitute having C—N, C—O, C—S and other bonds.

NEW BICYCLIC COMPOUND FOR MODULATING G PROTEIN-COUPLED RECEPTORS

The present invention relates to a bicyclic compound for modulating G protein-coupled receptors. The inventive compound provides preventing or treating a disease associated with the modulation of G protein-coupled receptors, particularly GPR119 G protein-coupled receptors.

GPR119 AGONISTS FOR THE TREATMENT OF DIABETES AND RELATED DISORDERS

The present invention relates to novel compounds that are useful in the treatment of metabolic disorders, particularly Type II diabetes mellitus and related disorders, and also to the methods for the making and use of such compounds.