83282-08-0

Basic information

• Product Name: 6-methyl-N-(1H-tetrazol-5-yl)-2-pyridinecarboxamide
• Synonyms: 6-methyl-N-(1H-tetrazol-5-yl)-2-pyridinecarboxamide
• CAS NO: 83282-08-0
• Molecular Formula: C8H8N6O
• Molecular Weight: 204.1887
• Mol File: 83282-08-0.mol

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.58g/cm³
• Refractive Index: 1.763
• CAS DataBase Reference: 6-methyl-N-(1H-tetrazol-5-yl)-2-pyridinecarboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 6-methyl-N-(1H-tetrazol-5-yl)-2-pyridinecarboxamide(83282-08-0)
• EPA Substance Registry System: 6-methyl-N-(1H-tetrazol-5-yl)-2-pyridinecarboxamide(83282-08-0)

Safety Data

• Hazardous Substances Data: 83282-08-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H8N6O/c1-5-3-2-4-6(9-5)7(15)10-8-11-13-14-12-8/h2-4,8H,1H3,(H,10,15)

Upstream product

• 4418-61-5 5-aminotetrazole 
• 126125-54-0 6-methyl-pyridine-2-carbonyl chloride 
• 934-60-1 6-methyl-2-pyridinecarboxylic acid 
• 87884-49-9 6-methylpyridine-2-carboxylic acid hydrochlorid salt 

Relevant articles and documents

Antiallergic agents. III. N-(1H-tetrazol-5-yl)-2-pyridinecarboxamides

A series of N-tetrazolylpyridinecarboxamides was prepared and evaluated for antiallergic activity by the passive cutaneous anaphylaxis assay. From the structure-activity relationships of this class of compounds, it was revealed that the N-tetrazolylcarbamoyl group as an acidic functionality is required to be at the 2-position of the pyridine nucleus and that the phenyl group as a substituent is not necessarily required for activity. 6-Methyl-N-(1H-tetrazol-5-yl)-2-pyridinecarboxamide showed good oral activity and low toxicity.

2-Pyridinecarboxamide derivatives compositions containing same and method of using same

A 2-pyridinecarboxamide derivative of the formula: STR1 wherein R1 is hydrogen, lower alkyl, lower alkoxy, halogen, lower alkyl-thio or nitro and is in the 3rd-, 4th- or 5th-position of the pyridyl group, and R2 is hydrogen, lower alkyl, lower alkoxy, phenoxy, phenyl-lower alkyl, phenyl-lower alkenyl, or halogen. Said 2-pyridinecarboxamide derivative (I) or a pharmaceutically acceptable salt thereof is useful as an anti-allergic agent.