83285-69-2Relevant academic research and scientific papers
Synthesis of mesoionic 3-aryl(hetaryl)-1,2,3,4-oxatriazol-5-ones based on N-aryl-and N-hetarylhydrazones of bromonitroformaldehyde
Shevelev,Dalinger,Gulevskaya,Cherkasova,Vinogradov,Ugrak,Starosotnikov
, p. 363 - 373 (1999)
Dehydrobromination of N-arylhydrazones of bromonitroformaldehyde (at 20°C) in the presence of alkali and ammonium salts of strong mineral acids, HNO3, silica gel, and Al2O3 forms mesoionic 3-aryl-1,2,3,4-oxatriazol-5-ones
Preliminary Studies of Mesoionic 3-(Substituted-aryl)-ψ-oxatriazoles as Potential Antihypertensive Agents
Lund, Mary Q.,Kier, Lemont B.,Glennon, Richard A.,Egle, John L.
, p. 1503 - 1505 (2007/10/02)
Several mesoionic 3-(substituted-aryl)-ψ-oxatriazole derivatives were prepared and evaluated as potential antihypertensive agents. 3-(4-Methylphenyl)-ψ-oxatriazole was found to produce a significant hypotensive effect in rats, which was characterized by a
