83299-97-2Relevant academic research and scientific papers
IONIZABLE CATIONIC LIPIDS
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Paragraph 0165, (2013/10/21)
Disclosed herein are novel compounds, pharmaceutical compositions comprising such compounds and related methods of their use. The compounds described herein are useful, e.g., as liposomal delivery vehicles to facilitate the delivery of encapsulated polynu
Antibacterial 16-membered ring macrolides containing olefins at C-20
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, (2008/06/13)
The present invention relates to C-20 olefin derivatives of 16-membered macrolide antibiotics repromicin, rosaramicin, 5-mycaminosyltylonolide, desmycosin, lactenocin, O-demethyllactenocin, 4'-deoxymycaminosyltylonolide and 23-deoxymycaminosyltylonolide, which are useful against bacterial and mycoplasmic pathogens in animals. Also claimed are a pharmaceutical composition of such derivatives and their use in treating bacterial and mycoplasmic infections in animals.
PREPARATION DE SELS D'AMINOALKYLPHOSPHONIUMS
Dantas, T. N. de Castro,Laval, J. P.,Lattes, A.
, p. 97 - 106 (2007/10/02)
Three synthetic methods have been applied to prepare amino phosphonium salts: (C6H5)3P+-(CH2)n-N-.The best ways have been determined for different n values and different substituents on the nitrogen atom.In all cases, yields are better with n=3, but no intramolecular stabilization has been detected.
