51498-40-9

Basic information

• Product Name: (4E)-N,N-dimethyl-5-phenylpent-4-en-1-amine
• CAS NO: 51498-40-9
• Molecular Formula: C₁₃H₁₉N
• Molecular Weight: 189.2967
• Mol File: 51498-40-9.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 288°C at 760 mmHg
• Flash Point: 116.9°C
• Density: 0.929g/cm³
• Vapor Pressure: 0.00239mmHg at 25°C
• Refractive Index: 1.544
• CAS DataBase Reference: (4E)-N,N-dimethyl-5-phenylpent-4-en-1-amine(CAS DataBase Reference)
• NIST Chemistry Reference: (4E)-N,N-dimethyl-5-phenylpent-4-en-1-amine(51498-40-9)
• EPA Substance Registry System: (4E)-N,N-dimethyl-5-phenylpent-4-en-1-amine(51498-40-9)

Safety Data

• Hazardous Substances Data: 51498-40-9(Hazardous Substances Data)

Usage

General Description

The chemical (4E)-N,N-dimethyl-5-phenylpent-4-en-1-amine, also known as 4DAMP, is a tertiary amine compound with the molecular formula C13H19N. It is a cholinergic antagonist and is used in scientific research to study the muscarinic acetylcholine receptor. 4DAMP has been shown to block the binding of certain ligands to these receptors, making it a valuable tool in studying the physiological and pharmacological effects of muscarinic acetylcholine signaling. Additionally, it may have potential applications in the development of new pharmaceutical drugs targeting this receptor system. However, further research is needed to fully understand the potential uses and effects of this compound.

Upstream product

• 118087-39-1 2-Methyl-1,3,4,5,6,11a-hexahydro-2H-2-benzazonine 
• 100-52-7 benzaldehyde 
• 83299-97-2 bromure de N,N-dimethylamino-4 butyltriphenylphosphonium 
• 50-00-0 formaldehyd 
• 122333-64-6 trans-N-Methyl-5-phenyl-4-penten-1-amine 
• 118087-36-8 2-Phenyl-1-trimethylsilanylmethyl-piperidine 
• 3466-80-6 2-phenylpiperidine 
• 118087-37-9 1-Methyl-2-phenyl-1-trimethylsilanylmethyl-piperidinium; iodide 
• 21087-29-6 trans-3-phenylprop-2-enyl chloride 
• 22768-07-6 (E)-ethyl 5-phenylpent-4-enoate 
• 63082-55-3 diethyl (E)-cinnamyl malonate 
• 19070-16-7 3-(N,N-dimethylamino)propylmagnesium chloride 
• 103-64-0 bromostyrene 
• 51498-40-9 trans-N,N-dimethyl-5-phenyl-4-penten-1-amine 

Downstream Products

• 3909-96-4 (1E,3E)-1-phenyl-1,3-pentadiene 
• 55666-17-6 (1E)-1,4-pentadienylbenzene 
• 62101-01-3 N,N-dimethyl-5-phenylpentan-1-amine 
• 55666-19-8 E-1-Trimethylammonio-5-phenylpenten-4 
• 51498-40-9 cis-N,N-dimethyl-5-phenyl-4-penten-1-amine 

Relevant articles and documents

Iron thiolate complexes: Efficient catalysts for coupling alkenyl halides with alkyl grignard reagents

Ironing out the kinks: Efficient new catalytic systems based on iron thiolates are described for the iron-catalyzed cross-coupling of alkyl Grignard reagents with alkenyl halides (see scheme). The reaction is highly chemo- and stereoselective. With this new procedure, the use of N-methylpyrrolidone as a co-solvent is no longer required. Copyright

Chain-length- and solvent-dependent intramolecular proton transfer in styrene-amine exciplexes

The photochemical and photophysical behavior of several ((N,N-dimethylamino)alkyl)styrenes in which the amino group is attached to the styrene α- or β-carbon by a methyl, ethyl, propyl, or butyl polymethylene chain has been investigated. Efficient intramolecular addition of an aminomethyl C-H to styrene is observed in nonpolar solvents for the (aminoethyl)styrenes, and addition of an aminomethylene C-H is observed for the (aminobutyl)styrenes. However, the (aminoethyl)- and (aminopropyl)styrenes do not undergo intramolecular addition reactions. Both the reactive and unreactive (aminoalkyl)styrenes form fluorescent singlet exciplexes in nonpolar and polar solvents. The resuls of exciplex and product quenching by an added primary amine indicate that the fluorescent exciplex is an intermediate in the addition reactions of the (aminoalkyl)styrenes. Activation parameters for both exciplex formation and exciplex proton transfer have been determined. Highly regioselective intramolecular proton transfer is proposed to occur via least motion pathways from the lowest energy folded conformations of the singlet exciplex intermediates in nonpolar solvents. The solvent dependence of exciplex proton transfer, fluorescence, intersystem crossing, and nonradiative decay is attributed to a change in exciplex conformation from folded in nonpolar solvents to extended in solvents more polar than diethyl ether.

Conjugated-triene intermediates in the Sommelet-Hauser rearrangement of cyclic 1-methyl-2-phenylammonium 1-methylides

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