833-38-5

Basic information

• Product Name: <4-Methyl-cyclohex-3-enyl>-phenyl-keton
• Synonyms: <4-Methyl-cyclohex-3-enyl>-phenyl-keton
• CAS NO: 833-38-5
• Molecular Weight: 200.28
• Mol File: 833-38-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: <4-Methyl-cyclohex-3-enyl>-phenyl-keton(CAS DataBase Reference)
• NIST Chemistry Reference: <4-Methyl-cyclohex-3-enyl>-phenyl-keton(833-38-5)
• EPA Substance Registry System: <4-Methyl-cyclohex-3-enyl>-phenyl-keton(833-38-5)

Safety Data

• Hazardous Substances Data: 833-38-5(Hazardous Substances Data)

Upstream product

• 131510-70-8 (2-Methyl-2-vinyl-cyclobutyl)-phenyl-methanone 
• 833-36-3 α-(4-Methyl-cyclohex-3-enyl)-benzylalkohol 
• 7560-64-7 4-methyl-cyclohex-3-enecarbaldehyde 
• 768-03-6 Phenyl vinyl ketone 
• 78-79-5 isoprene 

Downstream Products

• 836-89-5 1-<4-Methyl-cycohex-3-enyl>-1-phenyl-prop-2-in-1-ol 

Relevant articles and documents

Diels-Alder/thiol-olefin co-oxygenation approach to antimalarials incorporating the 2,3-dioxabicyclo[3.3.1]nonane pharmacophore

A Diels-Alder/thiol-olefin co-oxygenation approach to the synthesis of novel bicyclic endoperoxides 17a-22b is reported. Some of these endoperoxides (e.g., 17b, 19b, 22a and 22b) have potent nanomolar in vitro antimalarial activity equivalent to that of the synthetic antimalarial agent arteflene. Iron(II)-mediated degradation of sulfone-endoperoxide 19b and spin-trapping with TEMPO provide a spin-trapped adduct 25 indicative of the formation of a secondary carbon centered radical species 24. Reactive C-radical intermediates of this type may be involved in the expression of the antimalarial effect of these bicyclic endoperoxides.