833-68-1 Usage
Uses
Used in Pharmaceutical Synthesis:
6-Acetamidocoumarin is utilized as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure and properties make it a versatile building block for the creation of new drug candidates, contributing to the advancement of medicinal chemistry.
Used in Medicinal Research:
In the field of medicinal research, 6-Acetamidocoumarin serves as a fluorescent probe, enabling the investigation of enzyme kinetics and protein interactions. Its ability to emit fluorescence upon binding with enzymes or proteins provides a means to monitor and analyze these interactions, aiding in the understanding of biological mechanisms and the development of targeted therapies.
Used in Biological Research:
6-Acetamidocoumarin is employed in biological research as a tool to study molecular-level processes. Its fluorescent properties allow researchers to track and visualize the behavior of enzymes and proteins, providing insights into their functions and interactions within complex biological systems.
Check Digit Verification of cas no
The CAS Registry Mumber 833-68-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 8,3 and 3 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 833-68:
(5*8)+(4*3)+(3*3)+(2*6)+(1*8)=81
81 % 10 = 1
So 833-68-1 is a valid CAS Registry Number.
InChI:InChI=1/C11H9NO3/c1-7(13)12-9-3-4-10-8(6-9)2-5-11(14)15-10/h2-6H,1H3,(H,12,13)
833-68-1Relevant academic research and scientific papers
Gold(I)-Catalyzed Intramolecular Hydroarylation of Phenol-Derived Propiolates and Certain Related Ethers as a Route to Selectively Functionalized Coumarins and 2 H-Chromenes
Cervi, Aymeric,Vo, Yen,Chai, Christina L. L.,Banwell, Martin G.,Lan, Ping,Willis, Anthony C.
, p. 178 - 198 (2020/12/22)
Methods are reported for the efficient assembly of a series of phenol-derived propiolates, including the parent system 56, and their Au(I)-catalyzed cyclization (intramolecular hydroarylation) to give the corresponding coumarins (e.g., 1). Simple syntheses of natural products such as ayapin (144) and scoparone (145) have been realized by such means, and the first of these subject to single-crystal X-ray analysis. A related process is described for the conversion of propargyl ethers such as 156 into the isomeric 2H-chromene precocene I (159), a naturally occurring inhibitor of juvenile hormone biosynthesis.
