833445-84-4

Basic information

• Product Name: ALLYL 5-(BROMOMETHYL)ISOXAZOLE-3-CARBOXYLATE
• Synonyms: ALLYL 5-(BROMOMETHYL)ISOXAZOLE-3-CARBOXYLATE
• CAS NO: 833445-84-4
• Molecular Formula: C8H8BrNO3
• Molecular Weight: 246.06
• Mol File: 833445-84-4.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: ALLYL 5-(BROMOMETHYL)ISOXAZOLE-3-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ALLYL 5-(BROMOMETHYL)ISOXAZOLE-3-CARBOXYLATE(833445-84-4)
• EPA Substance Registry System: ALLYL 5-(BROMOMETHYL)ISOXAZOLE-3-CARBOXYLATE(833445-84-4)

Safety Data

• Hazardous Substances Data: 833445-84-4(Hazardous Substances Data)

Upstream product

• 123770-62-7 ethyl 5-(hydroxymethyl)isoxazole-3-carboxylate 
• 139297-56-6 5-(hydroxymethyl)-1,2-oxazole-3-carboxylic acid 
• 833445-83-3 3-allyloxycarbonyl-5-hydroxymethylisoxazole 

Relevant articles and documents

Novel 1β-methylcarbapenems with isoxazoloethenyl moieties containing carboxylic acid sodium salt

The synthesis of novel 1β-methylcarbapenems 1a,b having sodium 5-(3- and 5-carboxylic acid)isoxazoloethenyl moieties at C-5 position of pyrrolidine ring and their biological evaluation are described. Both compounds showed potent and well-balanced antibacterial activity as well as high stability to DHP-I. The selected sodium 3-carboxylic acid derivative 1a possessed excellent DHP-I stability and advanced pharmacokinetic parameters in comparison with 2 and meropenem. The synthesis of novel 1β-methylcarbapenems 1a,b having sodium 5-(3- and 5-carboxylic acid)isoxazoloethenyl moieties at C-5 position of pyrrolidine ring and their biological evaluation are described. Both compounds showed potent and well-balanced antibacterial activity as well as high stability to DHP-I. The selected sodium 3-carboxylic acid derivative 1a possessed excellent DHP-I stability and advanced pharmacokinetic parameters in comparison with 2 and meropenem.