83385-82-4Relevant academic research and scientific papers
Nuclear versus side-chain bromination of 4-methoxy toluene by an electrochemical method
Kulangiappar,Anbukulandainathan,Raju
, p. 2494 - 2502 (2014)
GRAPHICAL ABSTRACT The electrochemical bromination of 4-methoxy toluene by two-phase electrolysis yields 3-bromo 4-methoxy toluene at first, which subsequently undergoes side-chain bromination to give 3-bromo 4-methoxy benzyl bromide as a final product in 86% yield. The two-phase electrolysis consists of 25-50% NaBr as aqueous electrolyte and CHCl3 containing aromatic compound as organic phase. The reaction temperature is maintained at 10-25 °C. The probable orientation of bromine atom in an alkyl aromatic compound (nuclear versus side chain) is explained from the experimental result.
Restricted Rotation Involving the Tetrahedron Carbon. XLIII. Buttressing Effect on Rotational Barriers in Bromine-substituted 9-(2-Methoxy-4,6-dimethylphenyl)fluorenes
Aoki, Masahiro,Nakamura, Mikio,Oki, Michinori
, p. 2512 - 2515 (2007/10/02)
9-(2-Methoxy-4,6-dimethylphenyl)fluorenes carrying one or two bromo groups on the phenyl ring were prepared and the buttressing effect on the rotational barrier about the C9-Cph bond were investigated.The free energies of activation
