83388-22-1

Upstream product

• 91714-09-9 7-(4-fluorobenzoyl)-5-methyl-3-methylthioindolin-2-one 
• 91713-56-3 2-amino-5-methylphenyl 4-fluorophenyl ketone 

Downstream Products

• 91714-06-6 5-Methyl-7-[4-(methylthio)benzoyl]-indolin-2-one 
• 83388-21-0 Sodium; [2-amino-3-(4-fluoro-benzoyl)-5-methyl-phenyl]-acetate 
• 91741-88-7 Sodium; [2-amino-5-methyl-3-(4-methylsulfanyl-benzoyl)-phenyl]-acetate 

Relevant academic research and scientific papers

2-Amino-3-(alkylthiobenzoyl)-phenylacetic acids

Novel 2-amino-3-(alkylthiobenzoyl)phenylacetic acids, esters and metal salts have the formula: STR1 wherein R is hydrogen or lower alkyl, R1 is hydrogen, lower alkyl or pharmaceutically acceptable metal cation, R2 is hydrogen, haloge

Antiinflammatory agents. 3. Synthesis and pharmacological evaluation of 2-amino-3-benzoylphenylacetic acid and analogues

A series of substituted derivatives of 2-amino-3-benzoylphenylacetic acid (amfenac) has been synthesized and evaluated for antiinflammatory, analgesic, and cyclooxygenase inhibiting activity. Several derivatives including 4'-chloro, 4'-bromo and 5-chloro, 4'-bromo were more potent than indomethacin in these assays.