91713-56-3Relevant articles and documents
Efficient Friedel–Crafts benzoylation of aniline derivatives with 4-fluorobenzoyl chloride using copper triflate in the synthesis of aminobenzophenones
Tran, Phuong Hoang,Phung, Huy Quang,Hansen, Poul Erik,Tran, Hai Ngoc,Le, Thach Ngoc
, p. 893 - 901 (2016/07/06)
ABSTRACT: An efficient pathway for the synthesis of the aminobenzophenone derivatives via Friedel–Crafts benzoylation using copper triflate as catalyst is proposed. New derivatives are synthesized. The copper triflate could be easily recovered and reused without loss of catalytic activity. Both the use of ionic liquids and microwave heating turned out to be fruitful.
Design and Synthesis of 4-Azaindoles as Inhibitors of p38 MAP Kinase
Trejo, Alejandra,Arzeno, Humberto,Browner, Michelle,Chanda, Sushmita,Cheng, Soan,Comer, Daniel D.,Dalrymple, Stacie A.,Dunten, Pete,Lafargue, JoAnn,Lovejoy, Brett,Freire-Moar, Jose,Lim, Julie,McIntosh, Joel,Miller, Jennifer,Papp, Eva,Reuter, Deborah,Roberts, Rick,Sanpablo, Florentino,Saunders, John,Song, Kyung,Villasenor, Armando,Warren, Stephen D.,Welch, Mary,Weller, Paul,Whiteley, Phyllis E.,Zeng, Lu,Goldstein, David M.
, p. 4702 - 4713 (2007/10/03)
Inhibition of the biosynthesis of proinflammatory cytokines such as tumor necrosis factor and interleukin-1 via p38 has been an approach toward the development of a disease modifying agent for the treatment of chronic inflammation and autoimmune diseases.
