83390-26-5Relevant academic research and scientific papers
Mechanism of an Interesting Ring-Contraction Reaction of a Class of Carbocyclic trans-Dibromides and Stereoisomeric Bromohydrins through Solvolysis
Mandal, Asok N.,Bhattacharya, Sudin,Raychaudhuri, Swadesh R.,Chatterjee, Amareshwar
, p. 2856 - 2876 (2007/10/02)
An efficient ring contraction of the trans-dibromides and the bromohydrins (1a-f) through solvolysis under neutral conditions to the aldehydes (3a-d) in good to excellent yields is reported.The role of substituent, influence of stereochemistry, and the effect of ring size on the case of this interesting ring contraction reaction are clearly demonstrated from the results, tabulated in Table 1; a probable mechanism for ring contraction is presented.
An Efficient Procedure for the Preparation of a Class of α-Carboxy-γ-Lactones, and Studies on their Transformation to α-Methylene Derivatives.
Bhattacharya, Sudin,Chaudhuri, Swadesh R. Ray,Chatterjee, Amareshwar
, p. 1429 - 1460 (2007/10/02)
Attempted preparation of the bromohydrins (5a-b) gave interesting results.Ring opening of epoxides (1) and bromohydrins (5), the precursors of (1), with diethyl malonate anion under refluxing benzene has been shown to be the method of choice for the preparation of lactonic esters (acids)(3) in excellent yields.Methylenation of the lactonic acids provided the α-methylene-γ-lactones (4a-d).A possible pathway for the synthesis of the cis-lactones (22a-c) has also been investigated briefly.
AN INTERESTING RING CONTRACTION OF A CLASS OF BROMOHYDRINS AND TRANS-DIBROMIDES
Bhattacharya, S.,Mandal, A. N.,Chaudhuri, S. R. Ray,Chatterjee, A.
, p. 3007 - 3010 (2007/10/02)
An efficient ring contraction of stereoisomeric 1,2-benzo-4-bromo-3-hydroxycyclohept-1-ene and their derivatives (1a-e) to (2a-c) is reported, and a probable mechanism for this ring contraction has been suggested.
