83393-23-1 Usage
Uses
Used in Pharmaceutical Research and Development:
8-(Phenylmethyl)-8-azabicyclo[3.2.1]octan-3-one hydrochloride is used as a research compound for its potential applications in the field of medicine and pharmacology. Its unique chemical structure and pharmacological properties make it an interesting candidate for further exploration and development in the pharmaceutical industry.
Used in the Treatment of Neurological Disorders:
8-(Phenylmethyl)-8-azabicyclo[3.2.1]octan-3-one hydrochloride is used as a potential therapeutic agent for the treatment of various neurological disorders. Its behavioral effects on the central nervous system have been studied, indicating its potential to alleviate symptoms and improve the quality of life for patients suffering from such conditions.
Used in Experimental Studies:
8-(Phenylmethyl)-8-azabicyclo[3.2.1]octan-3-one hydrochloride is used as an experimental compound in various research studies. Its unique properties and potential applications in medicine and pharmacology make it a valuable tool for scientists and researchers to investigate its effects and mechanisms of action in different biological systems.
Check Digit Verification of cas no
The CAS Registry Mumber 83393-23-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,3,9 and 3 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 83393-23:
(7*8)+(6*3)+(5*3)+(4*9)+(3*3)+(2*2)+(1*3)=141
141 % 10 = 1
So 83393-23-1 is a valid CAS Registry Number.
InChI:InChI=1/C14H17NO.ClH/c16-14-8-12-6-7-13(9-14)15(12)10-11-4-2-1-3-5-11;/h1-5,12-13H,6-10H2;1H
83393-23-1Relevant academic research and scientific papers
Enhanced antibacterial activity of endo-nortropine substituted (C-7) fluoroquinolones against V. cholerae, S. aureus and B. subtilis
Salunke, Ramkrushna Ashok,Sidhu, Chandni,Kumar, Ashok,Pinnaka, Anil Kumar,Bansal, Baldev Raj,Chhibber, Manmohan
, p. 895 - 904 (2018/09/10)
Introduction: Bacterial infections account for maximum deaths worldwide than for any other single cause. Methods: Here in, we report a convenient synthesis of new fluoroquinolone molecules substituted with endo-nortropine and its derivatives at C-7position. All the synthesized molecules, when screened for their antibacterial activity by agar diffusion method against Vibrio cholerae, Bacillus subtilis, Staphylococcus aureus and Escherichia coli were found to be active against the first three strains. The shortlisted compounds in the series, RG and RO, were further evaluated to determine their MIC values by micro-dilution broth assay. Result & Conclusion: Compound RG was ten times more effective in case of S. aureus (15.0 nM), two times in case of V. cholerae (3.7 nM) and the same as that of standard drug Levofloxacin in case of Bacillus subtilis (7.8 nM). Compound RO also displayed an impressive MIC value (62.5 nM) in case of S. aureus as compared to control (125 nM). The results have been supported by in-silico docking studies, where increased hydrogen bonding interactions in case of RG as compared to standard drug levofloxacin with DNA gyrase (2XCT) of S. aureus resulted in decreased energy of the former.
