83393-68-4Relevant academic research and scientific papers
Synthesis of N-substituted 3-(2-aryl-2-oxoethyl)- 3-hydroxyindolin-2-ones and their conversion to N-substituted (E)-3-(2-aryl-2-oxoethylidene)-indolin-2-ones: Synthetic sequence, spectroscopic characterization and structures of four 3-hydroxy compounds an
Becerra, Diana,Castillo, Juan,Cobo, Justo,Glidewell, Christopher,Insuasty, Braulio
, p. 433 - 445 (2020/05/18)
An operationally simple and time-efficient approach has been developed for the synthesis of racemic N-substituted 3-(2-aryl-2-oxoethyl)-3-hydroxyindolin-2- ones by a piperidine-catalysed aldol reaction between aryl methyl ketones and N-alkylisatins. These
Iodine-Mediated C-H Functionalization of sp, sp2, and sp3 Carbon: A Unified Multisubstrate Domino Approach for Isatin Synthesis
Satish, Gandhesiri,Polu, Ashok,Ramar, Thangeswaran,Ilangovan, Andivelu
, p. 5167 - 5175 (2015/05/27)
(Chemical Equation Presented) Molecular iodine-promoted efficient construction of isatins from 2′-aminophenylacetylenes, 2′-aminostyrenes, and 2′-amino-β-ketoesters is developed via oxidative amidation of sp, sp2, and sp3 C-H bonds. The reaction involves consecutive iodination, Kornblum oxidation, and intramolecular amidation in a single reactor. The present method meets all of the atom and redox economy principles.
Potential anticonvulsants. V. The condensation of isatins with C-acetyl heterocyclic compounds
Popp
, p. 589 - 592 (2007/10/02)
A number of C-acetyl heterocyclic compounds were condensed with isatin and substituted isatins to give a series of 3-hydroxy-3-substituted oxindoles. The products from 2-acetylfuran and isatin, 2-acetylthiophene and isatin, and 2-acetylpyridine and 1-meth
