83397-89-1

Upstream product

• 165904-22-3 4,4,5,5-tetramethyl-2-phenethyl-1,3,2-dioxaborolane 
• 103-63-9 1-phenyl-2-bromoethane 
• 201230-82-2 carbon monoxide 
• 109-73-9 N-butylamine 
• 133595-52-5 diethyl 2,6-dimethyl-4-phenethyl-1,4-dihydropyridine-3,5-dicarboxylate 
• 4250-02-6 1-diazo-3-phenyl-2-propanone 
• 645-45-4 hydrocinnamic acid chloride 
• 2769-64-4 n-butyl isonitrile 

Relevant academic research and scientific papers

Stereoselective Synthesis of 3,5-Dihydroxypyrrolidin-2-ones Through a Photoinduced Multicomponent Reaction Followed by Dimerization

A photoinduced reaction between diazoketones, isocyanides and silanols, followed by aldol dimerization of the resulting multicomponent adduct, affords polyfunctionalized 3,5-dihydroxypyrrolidin-2-one heterocycles in a straightforward manner. Six new bonds

Manganese(III)-Promoted Double Carbonylation of Anilines Toward α-Ketoamides Synthesis

Employing anilines as nucleophiles in double carbonylation is a longstanding challenge. In this communication, a Mn(III)-promoted double carbonylation of alkylborates or Hantzsch esters with anilines toward the synthesis of α-ketoamides has been developed. By using easily available potassium alkyltrifluoroborates or Hantzsch esters as the starting material, and cheap and non-toxic Mn(OAc)3 ? 2H2O as the promotor, a broad range of alkyl α-ketoamide derivatives were synthesized in moderate to good yields with excellent selectivity. (Figure presented.).

Rapid synthesis of α-ketoamides using microwave irradiation- simultaneous cooling method

Microwave-assisted acyl chloride-isonitrile condensation and CaCO 3-mediated hydrolysis constitute a one-pot, 2-minute process to prepare α-ketoamides.