83440-02-2Relevant academic research and scientific papers
Preparation method and application of 9-position substituted di-functional-group berberine derivatives
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Paragraph 0035; 0036, (2017/07/22)
The invention provides a synthetic method of 9-position substituted di-functional-group berberine derivatives, and belongs to the field of drug synthesis. A pharmacological experiment proves that the derivatives have the drug activities of various values and have the absorbable performance which the other drugs do not have, and particularly the derivatives have the excellent effects of adjusting blood glucose and blood fat of rats suffering from type-II diabetes. The derivatives have the main effects that the oral glucose tolerance can be improved, insulin secretion can be promoted, insulin resistance can be improved, and the amount of triglyceride can be lowered.
