83467-04-3

Basic information

• Product Name: 1-methyl-2-(thio-p-toluoyl methylene)hexahydropyrimidine
• CAS NO: 83467-04-3
• Molecular Weight: 246.376
• Mol File: 83467-04-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-methyl-2-(thio-p-toluoyl methylene)hexahydropyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methyl-2-(thio-p-toluoyl methylene)hexahydropyrimidine(83467-04-3)
• EPA Substance Registry System: 1-methyl-2-(thio-p-toluoyl methylene)hexahydropyrimidine(83467-04-3)

Safety Data

• Hazardous Substances Data: 83467-04-3(Hazardous Substances Data)

Upstream product

• 104-87-0 4-methyl-benzaldehyde 
• 4271-96-9 1,2-dimethyl-1,4,5,6-tetrahydropyrimidine 

Relevant articles and documents

SYNTHESIS OF 1,1-DIAMINO-2-THIOACYLETHYLENES: A NOVEL C-THIOACYLATION BY THE WILLGERODT-KINDLER REACTION

A novel C-thioacylation reaction is described.Reaction of aromatic or heterocyclic aldehydes with 1-alkyl-2-methyl-1,4,5,6-tetrahydropyrimidine or 1-alkyl-2-methylimidazolidine in the presence of sulphur leads to the thioacylketeneaminals 6,10 or 12 in low to moderate yields.The structure of 6e was proved by S-methylation to 7e and acid-hydrolysis to the known 8e.Oxidative cyclization of 6 leads to the isothiazolo(2,3-a) pyrimidinium salts 13.